{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T03:37:08Z","timestamp":1785901028767,"version":"3.56.0"},"reference-count":29,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2017,2,9]],"date-time":"2017-02-09T00:00:00Z","timestamp":1486598400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animal Science Journal"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study was performed to evaluate effects of <jats:italic>Armillariella tabescens<\/jats:italic> (<jats:italic>A. tabescens<\/jats:italic>) on the growth performance and intestinal immune response and microflora in early\u2010weaned pigs when used as feed additive. <jats:italic>A. tabescens<\/jats:italic> mycelia were added to basal diets at concentrations of 0%, 0.1%, 0.3% or 0.9% (w\/w). A total of 144 commercial cross\u2010bred piglets were randomly allocated to one of these four diets and fed for 30\u00a0days. The growth performance of early\u2010weaned piglets displayed improvement with diets containing 0.1% and 0.3% dried mycelia powder from <jats:italic>A. tabescens<\/jats:italic>. Supplementing with 0.1% or 0.3% <jats:italic>A. tabescens<\/jats:italic> mycelia induced a 2.6\u2010 and three\u2010fold increase in secretory immunoglobulin A (sIgA) content in the jejunal mucosa, respectively, but had only a marginal effect on sIgA in the ileal mucosa. Expression of interleukin\u20102, interferon\u2010\u03b3, and tumor necrosis factor\u2010\u03b1 in the jejunal mucosa were elevated with <jats:italic>A. tabescens<\/jats:italic> mycelia administration. Increased amounts of <jats:italic>Lactobacillus<\/jats:italic> spp. and <jats:italic>Bifidobacterium<\/jats:italic> spp. in the jejunum, and decreased amounts of <jats:styled-content style=\"fixed-case\"><jats:italic>Escherichia coli<\/jats:italic><\/jats:styled-content> in the jejunum and ileum were observed with the administration of <jats:italic>A. tabescens<\/jats:italic>\u2010containing diets. This study demonstrated that <jats:italic>A. tabescens<\/jats:italic> had beneficial effects on the growth performance and intestinal microflora of early\u2010weaned pigs.<\/jats:p>","DOI":"10.1111\/asj.12765","type":"journal-article","created":{"date-parts":[[2017,2,10]],"date-time":"2017-02-10T00:36:39Z","timestamp":1486686999000},"page":"1388-1397","source":"Crossref","is-referenced-by-count":14,"title":["Effects of <i>Armillariella tabescens<\/i> mycelia on the growth performance and intestinal immune response and microflora of early\u2010weaned pigs"],"prefix":"10.1111","volume":"88","author":[{"given":"Wen\u2010Bin","family":"Chen","sequence":"first","affiliation":[{"name":"College of Animal Science and Technology Hunan Agricultural University  Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mao\u2010Ji","family":"Cheng","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology Anhui Agricultural University  Hefei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun\u2010Bo","family":"Tian","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology Zhongkai University of Agriculture and Engineering  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qin\u2010Hua","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology Hunan Agricultural University  Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology Hunan Agricultural University  Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei\u2010Jun","family":"Li","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology Hunan Agricultural University  Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Re\u2010Jun","family":"Fang","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology Hunan Agricultural University  Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,2,9]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2013.00222"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/17450390701780201"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-0929.2011.00924.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1631\/jzus.B1500147"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/1756-0500-6-340"},{"key":"e_1_2_5_7_1","volume-title":"New NRC nutrient requirements of swine. 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