{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T05:27:24Z","timestamp":1780378044488,"version":"3.54.1"},"reference-count":16,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2017,5,30]],"date-time":"2017-05-30T00:00:00Z","timestamp":1496102400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Aomori Research, Art and Culture Foundation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animal Science Journal"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Taurine lowers blood glucose levels and improves hyperglycemia. However, its effects on glucose transport in the small intestine have not been investigated. Here, we elucidated the effect of taurine on glucose absorption in the small intestine. In the oral glucose tolerance test, addition of 10\u00a0mmol\/L taurine suppressed the increase in hepatic portal glucose concentrations. To investigate whether the suppressive effect of taurine occurs via down\u2010regulation of active glucose transport in the small intestine, we performed an assay using the everted sac of the rat jejunum. Addition of taurine to the mucosal side of the jejunum suppressed active glucose transport via sodium\u2010glucose cotransporter 1 (<jats:styled-content style=\"fixed-case\">SGLT<\/jats:styled-content>1). After elimination of chloride ions from the mucosal solution, taurine did not show suppressive effects on active glucose transport. These results suggest that taurine suppressed the increase in hepatic portal glucose concentrations via suppression of<jats:styled-content style=\"fixed-case\">SGLT<\/jats:styled-content>1 activity in the rat jejunum, depending on chloride ions.<\/jats:p>","DOI":"10.1111\/asj.12829","type":"journal-article","created":{"date-parts":[[2017,5,30]],"date-time":"2017-05-30T09:42:04Z","timestamp":1496137324000},"page":"1763-1767","source":"Crossref","is-referenced-by-count":6,"title":["Effects of taurine on plasma glucose concentration and active glucose transport in the small intestine"],"prefix":"10.1111","volume":"88","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0000-141X","authenticated-orcid":false,"given":"Yo","family":"Tsuchiya","sequence":"first","affiliation":[{"name":"Department of Health and Nutrition Faculty of Home Economics Tohoku Women's College Hirosaki Aomori Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koichi","family":"Kawamata","sequence":"additional","affiliation":[{"name":"Department of Domestic Science Faculty of Domestic Science Tohoku Seikatsu Bunka University Sendai Miyagi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,5,30]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2004.08.017"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2008.164228"},{"key":"e_1_2_6_4_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0065-3101(24)00213-5","article-title":"Taurine: its biological role and clinical implications","volume":"32","author":"Chesney RW","year":"1985","journal-title":"Advances in Pediatrics"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00355.2002"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1966.sp008026"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.1992.72.1.101"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-33504-9_14"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/108.5.773"},{"key":"e_1_2_6_10_1","first-page":"997","article-title":"Chloride\u2010dependent intestinal transport of imino and beta\u2010amino acids in the guinea pig and rat","volume":"266","author":"Munck LK","year":"1994","journal-title":"American Journal of Physiology"},{"key":"e_1_2_6_11_1","first-page":"1154","article-title":"Specificity of the imino acid carrier in rat small intestine","volume":"266","author":"Munck BG","year":"1994","journal-title":"American Journal of Physiology"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/71.1.54"},{"key":"e_1_2_6_13_1","first-page":"22","article-title":"Sulfur in human nutrition and applications in medicine","volume":"7","author":"Parcell S","year":"2002","journal-title":"Alternative Medicine Review"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.3616607"},{"key":"e_1_2_6_15_1","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1242\/jeb.194.1.47","article-title":"Short\u2010term cell volume regulation in Mytilus californianus gill","volume":"194","author":"Silva AL","year":"1994","journal-title":"Journal of Experimental Biology"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.3177\/jnsv.61.502"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.200.2.287"}],"container-title":["Animal Science Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fasj.12829","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/asj.12829","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,24]],"date-time":"2024-06-24T12:10:50Z","timestamp":1719231050000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/asj.12829"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,30]]},"references-count":16,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1111\/asj.12829"],"URL":"https:\/\/doi.org\/10.1111\/asj.12829","archive":["Portico"],"relation":{},"ISSN":["1344-3941","1740-0929"],"issn-type":[{"value":"1344-3941","type":"print"},{"value":"1740-0929","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,30]]}}}