{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T01:21:18Z","timestamp":1769304078715,"version":"3.49.0"},"reference-count":33,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2017,6,6]],"date-time":"2017-06-06T00:00:00Z","timestamp":1496707200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["23450403"],"award-info":[{"award-number":["23450403"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animal Science Journal"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The effects of <jats:sc>l<\/jats:sc>\u2010<jats:styled-content style=\"fixed-case\">DOPA<\/jats:styled-content>, a precursor of dopamine (<jats:styled-content style=\"fixed-case\">DA<\/jats:styled-content>), and sulpiride, a D<jats:sub>2<\/jats:sub>\u2010type <jats:styled-content style=\"fixed-case\">DA<\/jats:styled-content> receptor blocker, on growth hormone (<jats:styled-content style=\"fixed-case\">GH<\/jats:styled-content>) and prolactin (<jats:styled-content style=\"fixed-case\">PRL<\/jats:styled-content>) secretion were investigated in steers. Eight Holstein steers (212.8\u00a0\u00b1\u00a07.8\u00a0kg body weight) were used. Lighting conditions were 12:12 L:D (lights on: 06.00\u201318.00\u00a0hours). Blood samplings were performed during the daytime (11.00\u201315.00\u00a0hours) and nighttime (23.00\u201303.00\u00a0hours). Intravenous injections of drugs or saline were performed at 12.00 hour for the daytime and 00.00\u00a0hour for the nighttime, respectively. Plasma <jats:styled-content style=\"fixed-case\">GH<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PRL<\/jats:styled-content> concentrations were determined by radioimmunoassay. <jats:sc>l<\/jats:sc>\u2010<jats:styled-content style=\"fixed-case\">DOPA<\/jats:styled-content> did not alter the <jats:styled-content style=\"fixed-case\">GH<\/jats:styled-content> secretion when it was injected at 12.00\u00a0hour (spontaneous <jats:styled-content style=\"fixed-case\">GH<\/jats:styled-content> level at its peak). On the other hand, <jats:sc>l<\/jats:sc>\u2010<jats:styled-content style=\"fixed-case\">DOPA<\/jats:styled-content> increased <jats:styled-content style=\"fixed-case\">GH<\/jats:styled-content> secretion at 00.00\u00a0hour (<jats:styled-content style=\"fixed-case\">GH<\/jats:styled-content> level at its trough). Injection of sulpiride suppressed <jats:styled-content style=\"fixed-case\">GH<\/jats:styled-content> secretion at 12.00\u00a0hour but did not affect <jats:styled-content style=\"fixed-case\">GH<\/jats:styled-content> levels at 00.00\u00a0hour. <jats:sc>l<\/jats:sc>\u2010<jats:styled-content style=\"fixed-case\">DOPA<\/jats:styled-content> inhibited and sulpiride stimulated <jats:styled-content style=\"fixed-case\">PRL<\/jats:styled-content> release during both periods. These results suggest that dopaminergic neurons have stimulatory action on <jats:styled-content style=\"fixed-case\">GH<\/jats:styled-content> secretion and inhibitory action on <jats:styled-content style=\"fixed-case\">PRL<\/jats:styled-content> secretion in cattle. In addition, injection time should be considered to evaluate the exact effects on <jats:styled-content style=\"fixed-case\">GH<\/jats:styled-content> secretion due to its ultradian rhythm of <jats:styled-content style=\"fixed-case\">GH<\/jats:styled-content> secretion in cattle.<\/jats:p>","DOI":"10.1111\/asj.12850","type":"journal-article","created":{"date-parts":[[2017,6,6]],"date-time":"2017-06-06T11:46:45Z","timestamp":1496749605000},"page":"1842-1848","source":"Crossref","is-referenced-by-count":7,"title":["The effects of <scp>l<\/scp>\u2010<scp>DOPA<\/scp> and sulpiride on growth hormone secretion at different injection times in Holstein steers"],"prefix":"10.1111","volume":"88","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4274-7933","authenticated-orcid":false,"given":"Etsuko","family":"Kasuya","sequence":"first","affiliation":[{"name":"Animal Environment and Health Unit Division of Animal Environment and Waste Management Research Institute of Livestock and Grassland Science National Agriculture and Food Research Organization Tsukuba Ibaraki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madoka","family":"Sutoh","sequence":"additional","affiliation":[{"name":"Animal Environment and Health Unit Division of Animal Environment and Waste Management Research Institute of Livestock and Grassland Science National Agriculture and Food Research Organization Tsukuba Ibaraki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken\u2010ichi","family":"Yayou","sequence":"additional","affiliation":[{"name":"Animal Environment and Health Unit Division of Animal Environment and Waste Management Research Institute of Livestock and Grassland Science National Agriculture and Food Research Organization Tsukuba Ibaraki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,6,6]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"Japanese Feeding Standard for Dairy Cattle","author":"Agriculture, Forestry and Fisheries Council (AFFRC)","year":"1999"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-53-6-1273"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-86-1-120"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(84)90051-X"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-104-6-1656"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo.143.4.8750"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00168768"},{"key":"e_1_2_6_9_1","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1159\/000318495","article-title":"Neurotransmitter modulation of the GHRH\u2010GH axis","volume":"38","author":"Garcia\u2010Tornadu I","year":"2010","journal-title":"Frontiers of Hormone Research"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1210\/er.19.6.717"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/27.8.383827"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/cen.12207"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj1954.16.581"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj1954.25.19"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-0929.2011.00949.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/asj.12037"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-47-3-480"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1159\/000126666"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-119-4-1712"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0739-7240(98)00011-3"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1159\/000124446"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj.49.145"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.1999.79.2.511"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1159\/000126101"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5673-12.2013"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1988.tb03690.x"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2826.2003.01009.x"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2014-1714"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3940(99)00245-1"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2011-1069"},{"key":"e_1_2_6_31_1","first-page":"137","article-title":"Imaging blood\u2010brain barrier function by using positron emission tomography to evaluate drug penetration into the brain","volume":"65","author":"Takano H","year":"2013","journal-title":"Brain and Nerve"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-98-3-562"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5953.299"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0739-7240(97)00031-3"}],"container-title":["Animal Science Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fasj.12850","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/asj.12850","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T19:07:18Z","timestamp":1696014438000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/asj.12850"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,6]]},"references-count":33,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1111\/asj.12850"],"URL":"https:\/\/doi.org\/10.1111\/asj.12850","archive":["Portico"],"relation":{},"ISSN":["1344-3941","1740-0929"],"issn-type":[{"value":"1344-3941","type":"print"},{"value":"1740-0929","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,6]]}}}