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Uterine tissue was subjectively collected on Day 20 and microscopically classified to four regions: endometrial stroma (ES), surface endometrial gland (EG), deep endometrial gland (DG), and myometrium (Myo). The cell proliferation marker, Ki\u201067, was quantified as labeling index (LI) in uterine regions, and tissues were immunostained to detect ESR2 followed by image analysis. The LI of ES, EG, and DG was greater (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009=\u20090.0018,\n                    <jats:italic>P<\/jats:italic>\n                    \u2009=\u20090.0005, and\n                    <jats:italic>P<\/jats:italic>\n                    \u2009=\u20090.0103; respectively) in heifers received FSH for 3\u2009days. The expression of ESR2 protein on ES and EG was greatest (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u20090.0001 and\n                    <jats:italic>P<\/jats:italic>\n                    \u2009=\u20090.0036, respectively) in FSH 3\u2009days\u2010treated group. Thus, FSH administration during proestrus stimulates uterine cell proliferation, and ESR2 expressions are affected by FSH during proestrus and differentially distributed in the uterine regions.\n                  <\/jats:p>","DOI":"10.1111\/asj.13621","type":"journal-article","created":{"date-parts":[[2021,8,27]],"date-time":"2021-08-27T05:38:38Z","timestamp":1630042718000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effects of FSH treatment and withdrawal during proestrus on uterine proliferation and steroid hormone receptor expression in beef heifers"],"prefix":"10.1111","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2634-7147","authenticated-orcid":false,"given":"Thanya","family":"Bunma","sequence":"first","affiliation":[{"name":"Department of Animal Science, Faculty of Agriculture Khon Kaen University  Khon Kaen 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