{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T12:41:01Z","timestamp":1789735261633,"version":"4.0.1"},"reference-count":46,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,11,27]],"date-time":"2022-11-27T00:00:00Z","timestamp":1669507200000},"content-version":"vor","delay-in-days":330,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31860660"],"award-info":[{"award-number":["31860660"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Animal Science Journal"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study investigated the effects of bioactive peptides derived from solid\u2010state fermentation of cottonseed meal on the growth performance, apparent dietary digestibility, serum biochemical parameters, protein metabolism, antioxidant activity, and immunity in yellow\u2010feathered broilers. A total of two hundred forty 21\u2010days\u2010old male broilers were randomly divided into four groups with six replicates per group. The control group received a basal diet and three experimental groups were fed diets with 1%, 2%, and 3% cottonseed meal bioactive peptides (CSBP) replacing equivalent protein of cottonseed meal in basic diet. Dietary supplementation of 2% and 3% CSBP increased the average daily weight gain, crude protein digestibility, total serum protein, and immunoglobulin (Ig) G contents in serum (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). The 3% CSBP increased albumin, total antioxidant capacity, spleen weight\/bodyweight, interleukin\u20106, and IgM, while reducing the feed to gain ratio, total cholesterol, urea nitrogen, total superoxide dismutase, glutathione peroxidase, and malondialdehyde contents in serum (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). The 2% CSBP diet increased <jats:italic>PepT1<\/jats:italic> expression in duodenum, jejunum, and ileum (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). The 1%, 2%, and 3% CSBP diets increased <jats:italic>S6kinase\u2010polypeptide\u20101<\/jats:italic> and <jats:italic>inositol\u20103\u2010hydroxylase<\/jats:italic> expression in chest and leg muscles (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). The CSBP addition in diets can improve growth performance, nutrient digestibility, protein metabolism, antioxidant, and immune capabilities of yellow\u2010feathered broilers.<\/jats:p>","DOI":"10.1111\/asj.13781","type":"journal-article","created":{"date-parts":[[2022,11,28]],"date-time":"2022-11-28T04:26:20Z","timestamp":1669609580000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Effects of bioactive peptides derived from cottonseed meal solid\u2010state fermentation on the growth, metabolism, and immunity of yellow\u2010feathered broilers"],"prefix":"10.1111","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7208-5240","authenticated-orcid":false,"given":"Jiancheng","family":"Liu","sequence":"first","affiliation":[{"name":"College of Animal Science Xinjiang Agricultural University  Urumqi China"},{"name":"College of Animal Science and Technology Shihezi University  Shihezi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanqin","family":"Luo","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology Shihezi University  Shihezi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyang","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology Shihezi University  Shihezi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Gao","sequence":"additional","affiliation":[{"name":"Institute of Applied Microbiology Xinjiang Academy of Agriculture Science, Xinjiang Special Environmental Microbiology Laboratory  Urumqi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenju","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology Shihezi University  Shihezi China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,11,27]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1017\/JAN.2017.6"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1017\/JAN.2018.1"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/foods6050035"},{"key":"e_1_2_7_5_1","volume-title":"Official methods of analysis","author":"AOAC","year":"1999"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.5851\/kosfa.2019.e82"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10989-019-09823-5"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00343-019-9152-3"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-50511-7"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12649-020-01066-6"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psj.2020.12.060"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.4024"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/10942912.2019.1640735"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40104-017-0153-9"},{"key":"e_1_2_7_15_1","first-page":"27","article-title":"Effects of canola bioactive peptides on performance, digestive enzyme activities, nutrient digestibility, intestinal morphology and gut microjlora in broiler chickens","volume":"4","author":"Karimzadeh S.","year":"2016","journal-title":"Poultry Science Journal"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tifs.2021.02.058"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/1828051X.2020.1844085"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aninu.2020.06.008"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2012.03.017"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10068-018-0414-1"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1006\/meth.2001.1262"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/ps\/86.3.582"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2017.08.030"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2016.03.048"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anifeedsci.2013.09.013"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10989-020-10086-8"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.procbio.2005.07.014"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.2141\/jpsa.44.119"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.3906\/vet-1410-65"},{"key":"e_1_2_7_30_1","volume-title":"Nutrient requirements of poultry","author":"NRC, National Research Council","year":"1994"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.3382\/ps\/pez346"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10989-019-09947-8"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10989-021-10168-1"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-001-0760-0"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1080\/19476337.2014.948072"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0043933916000258"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.5713\/ajas.2011.11381"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11250-019-02078-8"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psj.2021.101179"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anifeedsci.2011.06.012"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2021.129399"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1080\/09540105.2017.1311308"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2019.05.056"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsi.2020.01.008"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1631\/jzus.2006.B0690"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anifeedsci.2006.06.003"},{"key":"e_1_2_7_47_1","first-page":"135","volume-title":"Physiological importance and mechanisms of protein hydrolysate absorption","author":"Zhanghi B. M.","year":"2008"}],"container-title":["Animal Science Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/asj.13781","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/asj.13781","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/asj.13781","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T01:51:48Z","timestamp":1692582708000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/asj.13781"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":46,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["10.1111\/asj.13781"],"URL":"https:\/\/doi.org\/10.1111\/asj.13781","archive":["Portico"],"relation":{},"ISSN":["1344-3941","1740-0929"],"issn-type":[{"value":"1344-3941","type":"print"},{"value":"1740-0929","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"2022-04-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13781"}}