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In the first experiment, 11 adult Shiba goats were road transported twice with either a saline (control) or a commercial anti\u2010MS medication (Travelmin) injection at the first or second transportation. Almost all goats showed nausea\u2010like behavior, which was defined as pointing their heads downward, closing their eyes, and staying relatively still. These goats did not respond when they were touched during blood collection. The anti\u2010MS medication significantly reduced the total time spent in nausea\u2010like behavior (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.05) and tended to increase the frequency of escape attempts during blood collection (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.1). In a second experiment, the effects of the anti\u2010MS medication were examined in goats held under normal housing. The anti\u2010MS medication increased the time spent feeding (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.01) and reduced the time spent in rumination (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.05) but did not change the frequency of lying down nor plasma cortisol concentrations. Our results indicate that the nausea\u2010like behavior in transported goats might be induced, at least in part, by regulatory mechanisms similar to the MS.<\/jats:p>","DOI":"10.1111\/asj.13936","type":"journal-article","created":{"date-parts":[[2024,3,14]],"date-time":"2024-03-14T23:18:15Z","timestamp":1710458295000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Transportation\u2010induced nausea\u2010like behavior in goats and the effects of anti\u2010motion sickness medication"],"prefix":"10.1111","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3617-1242","authenticated-orcid":false,"given":"Masato","family":"Aoyama","sequence":"first","affiliation":[{"name":"Department of Animal Science, Faculty of Agriculture Utsunomiya University  Utsunomiya\u2010shi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takumi","family":"Motegi","sequence":"additional","affiliation":[{"name":"Department of Animal Science, Faculty of Agriculture Utsunomiya University  Utsunomiya\u2010shi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Kaneta","sequence":"additional","affiliation":[{"name":"Department of Animal Science, Faculty of Agriculture Utsunomiya University  Utsunomiya\u2010shi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoei","family":"Sugita","sequence":"additional","affiliation":[{"name":"Department of Animal Science, Faculty of Agriculture Utsunomiya University  Utsunomiya\u2010shi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,3,14]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2006.01.008"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.67.1109"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.71.281"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-0929.2008.00559.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1344-3941.2003.00146.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/asj.13607"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1017\/S135772980001540X"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0962728600021151"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0007-1935(96)80011-X"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.applanim.2012.03.009"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2885.2008.00990.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani10040705"},{"key":"e_1_2_7_14_1","first-page":"873","article-title":"Sopite syndrome: A sometimes sole manifestation of motion sickness","volume":"47","author":"Graybiel A.","year":"1976","journal-title":"Aviation, Space, and Environmental Medicine"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1371\/annotation\/1c75cd5d-9dde-4ace-8524-a4980745e804"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2014.10.007"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.2527\/2005.8381845x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smallrumres.2005.03.005"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.110.171306"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2015.03.018"},{"key":"e_1_2_7_21_1","first-page":"123","article-title":"Effects of the experience of road transportation on the behavioral responses to it in goats","volume":"52","author":"Sanuka K.","year":"2016","journal-title":"Animal Behavioural Management"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1159\/000350185"},{"key":"e_1_2_7_23_1","first-page":"1213","article-title":"Motion sickness: Advances in pathogenesis, prediction, prevention, and treatment","volume":"77","author":"Shupak A.","year":"2006","journal-title":"Aviation, Space, and Environmental Medicine"},{"key":"e_1_2_7_24_1","first-page":"44","article-title":"A. 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