{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T22:53:40Z","timestamp":1773010420587,"version":"3.50.1"},"reference-count":42,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T00:00:00Z","timestamp":1737504000000},"content-version":"am","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T00:00:00Z","timestamp":1737504000000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Animal Science Journal"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>The aim of this study was to investigate changes in milk conditions and antimicrobial components in goats during 8\u2009weeks prepartum and 1\u2009week postpartum. Milk was collected weekly from seven prepartum goats 8\u2009weeks before the due day, immediately, and 1\u2009week after parturition. Milk color scores and the concentration of antimicrobial components (cathelicidin\u20107 and S100A8) were significantly increased prepartum. There was a significant decrease in milk viscosity, color scores, somatic cell count, and antimicrobial components (lactoferrin and cathelicidin\u20102, 7) after kidding. However, S100A7 levels did not change throughout the prepartum or postpartum periods. These results indicate that concentrations of cathelicidin\u20107 and S100A8 differ between prepartum and postpartum periods. Therefore, these microbial components may play different roles in mastitis prevention. The findings of our study provide important information for regulating antimicrobial components in ruminants to prevent bacterial invasion during the peripartum period.<\/jats:p>","DOI":"10.1111\/asj.70029","type":"journal-article","created":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T21:23:42Z","timestamp":1737581022000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Antimicrobial Component Concentrations in the Milk of Peripartum Goats"],"prefix":"10.1111","volume":"96","author":[{"given":"Jin\u2010Kun","family":"Sun","sequence":"first","affiliation":[{"name":"Graduate School of Integrated Sciences for Life Hiroshima University  Higashi\u2010Hiroshima Hiroshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zi\u2010Long","family":"Liang","sequence":"additional","affiliation":[{"name":"Graduate School of Integrated Sciences for Life Hiroshima University  Higashi\u2010Hiroshima Hiroshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahiro","family":"Nii","sequence":"additional","affiliation":[{"name":"Graduate School of Integrated Sciences for Life Hiroshima University  Higashi\u2010Hiroshima Hiroshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6045-6729","authenticated-orcid":false,"given":"Naoki","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Graduate School of Integrated Sciences for Life Hiroshima University  Higashi\u2010Hiroshima Hiroshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9230-6346","authenticated-orcid":false,"given":"Naoki","family":"Isobe","sequence":"additional","affiliation":[{"name":"Graduate School of Integrated Sciences for Life Hiroshima University  Higashi\u2010Hiroshima Hiroshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,1,22]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"StatPearls","author":"Al\u2010Chalabi M.","year":"2024"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.14202\/vetworld.2018.562\u2010577"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani12111394"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.3923\/pjn.2008.303.307"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2013.05.139"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2007\u20100264"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.21521\/mw.6327"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2011.11.002"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/rda.13185"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1128\/iai.56.11.2774\u20102781.1988"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.S0022\u20100302(85)80936\u2010X"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri1180"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2008.07.020"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/af\/vfad014"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/asj.12808"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1262\/jrd.2014\u2010065"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1344\u20103941.2003.00128.x"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439\u20100531.2006.00792.x"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-031-08956-5_206-1"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2018\u201015543"},{"issue":"1","key":"e_1_2_7_22_1","first-page":"1","article-title":"Progesterone and Estradiol Profiles During Estrous Cycle and Gestation in Dwarf Goats (Capra hircus)","volume":"28","author":"Khanum S.","year":"2008","journal-title":"Pakistan Veterinary Journal"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2013\u20107615"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0260188"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anireprosci.2024.107430"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2003.82"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fbio.2021.100907"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010021\u201021533\u20105"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2017.06.060"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.2527\/2000.78suppl_326x"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smallrumres.2018.10.006"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2021\u201020564"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2018\u201015396"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetimm.2019.109972"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/asj.13926"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/asj.13780"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.S0022\u20100302(80)83112\u20102"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetimm.2022.110431"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10911\u2010022\u201009519\u20105"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2021.112472"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.54846\/jshap\/1322"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2014.06.013"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2014.01.029"}],"container-title":["Animal Science Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/asj.70029","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/asj.70029","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/asj.70029","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/asj.70029","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T21:12:46Z","timestamp":1773004366000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/asj.70029"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":42,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1111\/asj.70029"],"URL":"https:\/\/doi.org\/10.1111\/asj.70029","archive":["Portico"],"relation":{},"ISSN":["1344-3941","1740-0929"],"issn-type":[{"value":"1344-3941","type":"print"},{"value":"1740-0929","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2024-09-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70029"}}