{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T11:04:17Z","timestamp":1780743857124,"version":"3.54.1"},"reference-count":33,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,5,10]],"date-time":"2025-05-10T00:00:00Z","timestamp":1746835200000},"content-version":"vor","delay-in-days":129,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Animal Science Journal"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>High ambient temperature (HTa) in tropical conditions leads to evaporative heat dissipation by panting in lactating dairy goats. This panting causes respiratory hypocapnia, which increases the renal excretion of buffer molecules including sodium, potassium, and bicarbonate. In response, renal acid excretion decreases to preserve acidity. Besides hypocapnia, lactation and HTa could further deplete buffer molecules, enhancing acid preservation. This current study restored buffer molecules using high dietary cation and anion difference (DCAD) regimen and hypothesized that renal acid excretion during acute acid load would be increased in dairy goats fed high DCAD under HTa. To investigate this, 12 early\u2010lactating dairy goats were randomly assigned to two groups: control and DCAD, which were fed control and high\u2010DCAD diets, respectively, for 8\u2009weeks. Acute acid loading during HTa was induced by high\u2010dose ascorbic acid (AA) supplementation. During Weeks 4 and 8, the vehicle and AA were supplemented on the last two consecutive days of each week. The results showed that the renal acid excretion in DCAD group was higher than control group during high\u2010dose AA supplementation. Together with high renal buffer excretion by DCAD, an increased renal acid excretion may be partially mediated by an increase in buffer reserve.<\/jats:p>","DOI":"10.1111\/asj.70062","type":"journal-article","created":{"date-parts":[[2025,5,10]],"date-time":"2025-05-10T03:55:18Z","timestamp":1746849318000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["High Dietary Cation and Anion Difference Enhanced Renal Response to an Acute Acid Load of Lactating Goat Fed Under Tropical Conditions"],"prefix":"10.1111","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4738-2547","authenticated-orcid":false,"given":"Sapon","family":"Semsirmboon","sequence":"first","affiliation":[{"name":"Department of Physiology, Faculty of Veterinary Science Chulalongkorn University  Bangkok Thailand"},{"name":"Institute of Veterinary Physiology, Vetsuisse\u2010Faculty University of Zurich  Zurich Switzerland"},{"name":"Department of Physiology, Faculty of Medicine Kasetsart University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7865-9505","authenticated-orcid":false,"given":"Dang\u00a0Khoa","family":"do Nguyen","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Veterinary Science Chulalongkorn University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3207-0885","authenticated-orcid":false,"given":"Narongsak","family":"Chaiyabutr","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Veterinary Science Chulalongkorn University  Bangkok Thailand"},{"name":"Academy of Science Royal Society of Thailand  Bangkok Thailand"},{"name":"Queen Saovabha Memorial Institute Thai Red Cross Society  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3267-8599","authenticated-orcid":false,"given":"Sutthasinee","family":"Poonyachoti","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Veterinary Science Chulalongkorn University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5056-8548","authenticated-orcid":false,"given":"Thomas\u00a0A.","family":"Lutz","sequence":"additional","affiliation":[{"name":"Institute of Veterinary Physiology, Vetsuisse\u2010Faculty University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5500-1639","authenticated-orcid":false,"given":"Sumpun","family":"Thammacharoen","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Veterinary Science Chulalongkorn University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,10]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI103449"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.2527\/2006.844972x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010020\u201069915\u2010x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2021\u201021080"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0009\u20109120(72)80014\u20106"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.70.7.915"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2022\u201022142"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.S0022\u20100302(95)76853\u20109"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anifeedsci.2011.12.005"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani12233444"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.S0022\u20100302(84)81341\u20107"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0214665"},{"key":"e_1_2_7_14_1","volume-title":"Guyton and Hall Textbook of Medical Physiology","author":"Hall J. 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