{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T03:02:16Z","timestamp":1779678136212,"version":"3.53.1"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,5,24]],"date-time":"2026-05-24T00:00:00Z","timestamp":1779580800000},"content-version":"vor","delay-in-days":143,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Animal Science Journal"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    This study investigated the effects of orally administered sugars and casein, main components of whole milk, on plasma glucagon\u2010like peptide 1 (GLP\u20101) concentration in preweaning calves. In Experiment 1, calves received water (CON), 2.37% (w\/w) glucose (GLU), 2.37% galactose (GAL), or a mixed solution containing 2.37% each of glucose and galactose (GLU\u2009+\u2009GAL). In Experiment 2, calves received 4.5% (w\/w) lactose (LAC), 3.0% casein (CAS), or a mixed solution containing lactose at 4.5% and casein at 3.0% (LAC\u2009+\u2009CAS). Because baseline plasma GLP\u20101 and \u03b1\u2010amino nitrogen (AAN) concentrations varied greatly and correlated with postadministration mean concentrations, statistical analyses for these parameters included baseline values as covariates. In Experiment 1, glucose and insulin concentrations were higher in GLU and GLU\u2009+\u2009GAL than in CON (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001), whereas GLP\u20101 concentrations were lower in GAL than in other groups (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). In Experiment 2, glucose and insulin concentrations were higher in LAC and LAC\u2009+\u2009CAS, AAN concentrations were higher in CAS and LAC\u2009+\u2009CAS, and GLP\u20101 concentrations were higher in LAC, CAS, and LAC\u2009+\u2009CAS compared with CON (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). In conclusion, both lactose and casein promoted GLP\u20101 secretion in calves, although oral administration of glucose or galactose alone did not elicit a marked GLP\u20101 response.\n                  <\/jats:p>","DOI":"10.1111\/asj.70187","type":"journal-article","created":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T02:02:08Z","timestamp":1779674528000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Response of Plasma Glucagon\u2010Like Peptide 1 Concentration to Oral Administration of Lactose and Casein in Preweaning Calves"],"prefix":"10.1111","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2592-9022","authenticated-orcid":false,"given":"Yudai","family":"Inabu","sequence":"first","affiliation":[{"name":"Graduate School of Integrated Sciences for Life Hiroshima University  Higashihiroshima\u2010shi Hiroshima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Midori","family":"Satoh","sequence":"additional","affiliation":[{"name":"School of Applied Biological Science Hiroshima University  Higashihiroshima\u2010shi Hiroshima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4415-6181","authenticated-orcid":false,"given":"Taketo","family":"Obitsu","sequence":"additional","affiliation":[{"name":"Graduate School of Integrated Sciences for Life Hiroshima University  Higashihiroshima\u2010shi Hiroshima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5502-3451","authenticated-orcid":false,"given":"Toshihisa","family":"Sugino","sequence":"additional","affiliation":[{"name":"Graduate School of Integrated Sciences for Life Hiroshima University  Higashihiroshima\u2010shi Hiroshima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,24]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"E633","article-title":"Galactose Metabolism in Isolated Perfused Suckling\u2010Rat Liver","volume":"236","author":"Berman W.","year":"1979","journal-title":"American Journal of Physiology"},{"key":"e_1_2_7_3_1","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0739-7240(02)00210-2","article-title":"Glucagon\u2010Like Peptide 2 Function in Domestic Animals","volume":"24","author":"Burrin D. 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