{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T06:40:01Z","timestamp":1791700801109,"version":"4.3.4"},"reference-count":14,"publisher":"Wiley","issue":"1-2","license":[{"start":{"date-parts":[[2012,12,23]],"date-time":"2012-12-23T00:00:00Z","timestamp":1356220800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust Veterinary J"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine the significance of cyromazine resistance in blowfly larvae from a region where resistance has been previously confirmed and to measure susceptibility of the cyromazine\u2010resistant blowflies to ivermectin and spinosad.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Blowfly larvae from five properties located within 5\u2009km of where cyromazine\u2010resistant <jats:italic><jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>ucilia cuprina<\/jats:italic> were detected in 2011 were tested for resistance to cyromazine. The original cyromazine\u2010resistant \u2018<jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>immitabel\u2019 strain was reared for 13 generations on homogenised liver containing cyromazine at a concentration lethal to susceptible larvae. Larval development bioassays in which batches of neonate larvae were transferred onto homogenised bovine liver containing cyromazine or dicyclanil were used to determine whether the level of resistance had increased. The sensitivities of the \u2018<jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>immitabel\u2019 strain to ivermectin and spinosad were also measured.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Cyromazine\u2010resistant larvae were identified in samples from four of the five properties near to the site of the original resistance detection. The \u2018<jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>immitabel\u2019 strain responded to laboratory selection by becoming more resistant to cyromazine (8\u00d7) and to dicyclanil (3\u00d7). No larvae died after feeding on homogenate containing cyromazine at a concentration lethal to susceptible larvae. There was no cross\u2010resistance to ivermectin or spinosad in the \u2018<jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>immitabel\u2019 strain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The modest increases in resistance to cyromazine and dicyclanil following laboratory selection suggest that unless the situation worsens considerably, it is unlikely that this resistance will have a significant effect on flystrike protection provided by these insecticides if applied as directed on product labels. Moreover, cyromazine\u2010resistant larvae remained susceptible to ivermectin and spinosad.<\/jats:p><\/jats:sec>","DOI":"10.1111\/avj.12011","type":"journal-article","created":{"date-parts":[[2012,12,24]],"date-time":"2012-12-24T02:41:09Z","timestamp":1356316869000},"page":"61-64","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Response to laboratory selection with cyromazine and susceptibility to alternative insecticides in sheep blowfly larvae from the <scp>N<\/scp>ew <scp>S<\/scp>outh <scp>W<\/scp>ales <scp>M<\/scp>onaro"],"prefix":"10.1111","volume":"91","author":[{"given":"GW","family":"Levot","sequence":"first","affiliation":[{"name":"Elizabeth Macarthur Agricultural Institute NSW Department of Primary Industries  Private Bag 4008 Narellan New South Wales 2570 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,12,23]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.94.17.382"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/2121466b0"},{"key":"e_1_2_7_4_1","first-page":"43","article-title":"New high level resistance to diflubenzuron detected in the Australian sheep blowfly, Lucilia cuprina (Wiedemann) (Diptera: Calliphoridae)","volume":"31","author":"Levot GW","year":"2002","journal-title":"Gen Appl Ent"},{"key":"e_1_2_7_5_1","first-page":"27","article-title":"Differences in susceptibility to diflubenzuron between populations of the Australian sheep blowfly, Lucilia cuprina (Wiedemann) and their influence on flystrike protection","volume":"30","author":"Sales N","year":"2001","journal-title":"Gen Appl Ent"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.2012.00984.x"},{"key":"e_1_2_7_7_1","unstructured":"Bureau of Meteorology.http:\/\/www.bom.gov.au\/climate\/data\/index. 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