{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T01:31:00Z","timestamp":1775093460609,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,4,27]],"date-time":"2014-04-27T00:00:00Z","timestamp":1398556800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust Veterinary J"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Urinary tract infections caused by<jats:italic><jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>orynebacterium urealyticum<\/jats:italic>are uncommon in veterinary medicine. Encrusted cystitis, encrusted pyelitis and uroliths have been described as complications in humans, but only encrusted cystitis and cystoliths have been reported in dogs so far. Because<jats:italic><jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>. urealyticum<\/jats:italic>is usually resistant to all standard antibacterial drugs, antimicrobial treatment and elimination of this microorganism are challenging.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case report<\/jats:title><jats:p>An 11\u2010month\u2010old female spayed mixed\u2010breed dog was evaluated because of a<jats:italic><jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>. urealyticum<\/jats:italic>urinary tract infection, mineralisation within both renal pelvises and failure of antimicrobial treatment. Physical examination, haematology and biochemistry were unremarkable. Radiographic and ultrasonographic examinations confirmed bilateral nephrolithiasis. Voided uroliths were composed of 100% carbonate apatite. Urinalysis was indicative of bacterial infection. Aerobic culture of the urine and 16S<jats:styled-content style=\"fixed-case\">rRNA<\/jats:styled-content>sequencing identified significant growth of<jats:italic><jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>. urealyticum<\/jats:italic>and susceptibility testing revealed sensitivity to only vancomycin and linezolid.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Treatment with the oxazolidinone antibacterial, linezolid, in combination with a urine\u2010acidifying diet resulted in elimination of this multiresistant microorganism and complete resolution of nephrolithiasis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/avj.12168","type":"journal-article","created":{"date-parts":[[2014,4,28]],"date-time":"2014-04-28T01:25:16Z","timestamp":1398648316000},"page":"161-165","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Carbonate apatite nephrolithiasis associated with<i><scp>C<\/scp>orynebacterium urealyticum<\/i>urinary tract infection in a dog"],"prefix":"10.1111","volume":"92","author":[{"given":"SN","family":"Fleischhacker","sequence":"first","affiliation":[{"name":"Clinic of Small Animal Medicine Ludwig Maximilian University Munich Veterin\u00e4rstr. 13 80539 Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Horstmann","sequence":"additional","affiliation":[{"name":"Institute for Infectious Diseases and Zoonoses Ludwig Maximilian University Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Hartmann","sequence":"additional","affiliation":[{"name":"Clinic of Small Animal Medicine Ludwig Maximilian University Munich Veterin\u00e4rstr. 13 80539 Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Schubert","sequence":"additional","affiliation":[{"name":"Max von Pettenkofer\u2010Institute Department of Bacteriology Ludwig Maximilian University Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Dorsch","sequence":"additional","affiliation":[{"name":"Clinic of Small Animal Medicine Ludwig Maximilian University Munich Veterin\u00e4rstr. 13 80539 Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,4,27]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2005.226.1676"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2010.07.007"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2007.12.003"},{"key":"e_1_2_5_5_1","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1128\/jcm.30.5.1167-1169.1992","article-title":"Isolation of Corynebacterium group D2 from two dogs with urinary tract infections","volume":"30","author":"Elad D","year":"1992","journal-title":"J Clin Microbiol"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1995.tb15338.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2002.tb00077.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.35.10.2140"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2006.11.032"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)63009-X"},{"key":"e_1_2_5_11_1","unstructured":"Clinical and Laboratory Standards Institute.Performance standards for antimicrobial disk and dilution susceptibility tests for bacteria isolated from animals. 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