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Fibrinous pericarditis and pericardial effusion (<jats:styled-content style=\"fixed-case\">PE<\/jats:styled-content>) were recognised in each foal and considered as sequelae to systemic inflammatory response syndrome (<jats:styled-content style=\"fixed-case\">SIRS<\/jats:styled-content>) and suspected or confirmed septicaemia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical course and outcome<\/jats:title><jats:p>Diagnosis of pericarditis was made in two foals by echocardiographic examination and analysis of pericardial fluid, and during postmortem examination of the third foal. In both of the foals that underwent pericardiocentesis,<jats:styled-content style=\"fixed-case\">PE<\/jats:styled-content>was an exudate, no bacteria were identified on cytological analysis and bacterial culture was negative. Despite apparent response to treatment, two foals died 2 and 3 weeks, respectively, after discharge from hospital. One foal was euthanased during hospitalisation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion and clinical relevance<\/jats:title><jats:p>This report highlights the need to consider the development of pericarditis and<jats:styled-content style=\"fixed-case\">PE<\/jats:styled-content>in foals with<jats:styled-content style=\"fixed-case\">SIRS<\/jats:styled-content>and signs of cardiorespiratory dysfunction, and the requirement for protracted follow\u2010up to monitor for clinical resolution.<\/jats:p><\/jats:sec>","DOI":"10.1111\/avj.12238","type":"journal-article","created":{"date-parts":[[2014,9,2]],"date-time":"2014-09-02T03:08:58Z","timestamp":1409627338000},"page":"392-399","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Fibrinous pericarditis and pericardial effusion in three neonatal 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