{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T02:44:47Z","timestamp":1774320287177,"version":"3.50.1"},"reference-count":41,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,2,24]],"date-time":"2015-02-24T00:00:00Z","timestamp":1424736000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust Veterinary J"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:sec><jats:title>Case report<\/jats:title><jats:p>This report summarises the findings from a case of naturally\u2010occurring <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>urray <jats:styled-content style=\"fixed-case\">V<\/jats:styled-content>alley encephalitis in a 2\u2010year\u2010old filly presenting with acute onset of depression and weakness. Serum samples tested at the onset of clinical signs were negative for <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>endra and <jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>unjin virus antibodies, but positive for <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>urray <jats:styled-content style=\"fixed-case\">V<\/jats:styled-content>alley encephalitis virus (<jats:styled-content style=\"fixed-case\">MVEV<\/jats:styled-content>) using <jats:styled-content style=\"fixed-case\">IgM<\/jats:styled-content>\u2010capture <jats:styled-content style=\"fixed-case\">ELISA<\/jats:styled-content> (1\u2009:\u2009300 dilution). A virus neutralisation assay performed 4 weeks later confirmed a titre of 1\u2009:\u2009160. Sera collected in the weeks preceding neurological signs returned a negative titre for <jats:styled-content style=\"fixed-case\">MVEV<\/jats:styled-content> 2 weeks prior followed by a titre of 1:80 in the week prior to illness. Serological surveillance conducted on 67 co\u2010located horses returned a positive titre of 1\u2009:\u200920 in one in\u2010contact horse. There was no history of clinical disease in that horse. At 3 months after the onset of clinical signs in the index case, the filly continued to show mild facial paresis and hypermetria; the owners elected euthanasia and gave permission for necropsy. Histopathological analysis of the brain showed a mild meningoencephalitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The progression of a naturally\u2010occurring <jats:styled-content style=\"fixed-case\">MVEV<\/jats:styled-content> infection in a horse has been documented in this case.<\/jats:p><\/jats:sec>","DOI":"10.1111\/avj.12294","type":"journal-article","created":{"date-parts":[[2015,2,24]],"date-time":"2015-02-24T07:54:49Z","timestamp":1424764489000},"page":"53-57","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["A case of <scp>M<\/scp>urray <scp>V<\/scp>alley encephalitis in a 2\u2010year\u2010old <scp>A<\/scp>ustralian <scp>S<\/scp>tock <scp>H<\/scp>orse in south\u2010east <scp>Q<\/scp>ueensland"],"prefix":"10.1111","volume":"93","author":[{"given":"AJ","family":"Barton","sequence":"first","affiliation":[{"name":"School of Veterinary Science The University of Queensland  Gatton Queensland 4343 Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"NA","family":"Prow","sequence":"additional","affiliation":[{"name":"Australian Infectious Diseases Research Centre University of Queensland  St Lucia Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RA","family":"Hall","sequence":"additional","affiliation":[{"name":"Australian Infectious Diseases Research Centre University of Queensland  St Lucia Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Kidd","sequence":"additional","affiliation":[{"name":"School of Veterinary Science The University of Queensland  Gatton Queensland 4343 Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Bielefeldt\u2010Ohmann","sequence":"additional","affiliation":[{"name":"School of Veterinary Science The University of Queensland  Gatton Queensland 4343 Australia"},{"name":"Australian Infectious Diseases Research Centre University of Queensland  St Lucia Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,2,24]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid0704.017418"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1863-2378.2008.01208.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2004.10.010"},{"key":"e_1_2_6_5_1","first-page":"48","article-title":"Murray Valley encephalitis in Mt Isa, north Queensland. 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