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Serum biochemical testing was performed in addition to magnetic resonance imaging of the brain and cerebrospinal fluid analysis. Magnetic resonance imaging revealed a reduction in the number of sulci and gyri in addition to cortical thickening, resulting in a diagnosis of lissencephaly. The dog was treated with anticonvulsants and follow\u2010up information obtained from the referring veterinarian 11 months after diagnosis indicated that the dog had good seizure control.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This is the first report of lissencephaly in the Australian Kelpie and would suggest that some dogs with the condition can be managed with long\u2010term anticonvulsant medication.<\/jats:p><\/jats:sec>","DOI":"10.1111\/avj.12423","type":"journal-article","created":{"date-parts":[[2016,3,30]],"date-time":"2016-03-30T00:37:21Z","timestamp":1459298241000},"page":"107-110","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Lissencephaly in an adult Australian Kelpie"],"prefix":"10.1111","volume":"94","author":[{"given":"AR","family":"Fraser","sequence":"first","affiliation":[{"name":"Translational Research and Animal Clinical Trial Study (TRACTS) Group, Section 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