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Histopathological evaluation of bone marrow biopsy disclosed hypocellularity consistent with bone marrow failure. Concurrent hypocobalaminaemia was identified and treated with parenteral cyanocobalamin supplementation. Other differential diagnoses for pancytopenia, including infectious, toxic, immune\u2010mediated and neoplastic causes, were ruled out.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>The cat's erythrocyte, leucocyte and platelet counts normalised after 2\u2009months of cyanocobalamin supplementation, suggesting that pancytopenia may be a rare manifestation of feline cobalamin deficiency.<\/jats:p><\/jats:sec>","DOI":"10.1111\/avj.12570","type":"journal-article","created":{"date-parts":[[2017,4,26]],"date-time":"2017-04-26T08:16:49Z","timestamp":1493194609000},"page":"156-160","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Hypocobalaminaemia as a cause of bone marrow failure and pancytopenia in a cat"],"prefix":"10.1111","volume":"95","author":[{"given":"EL","family":"Stanley","sequence":"first","affiliation":[{"name":"Internal Medicine Department, The Animal Medical Center New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"AE","family":"Eatroff","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, The Animal Medical Center New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,4,26]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp1113996"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2013.01.025"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu5114521"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.1031155"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.12284"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-199101000-00006"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsap.12251"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.12152"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpc.12619"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.2008.01043.x"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.4066\/AMJ.2014.1872"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2001.tb02293.x"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2009.04.004"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2010.01027.x"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2010.00973.x"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2257.2006.00755.x"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hct142"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0950-3536(05)80215-X"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0149-2918(03)90096-8"},{"key":"e_1_2_8_21_1","first-page":"391","volume-title":"Diagnostic cytology and hematology of the dog and cat","author":"Cowell RL","year":"2010"},{"key":"e_1_2_8_22_1","first-page":"391","volume-title":"The Merck veterinary manual","author":"Kahn CM","year":"2010"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2005.227.263"}],"container-title":["Australian Veterinary Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Favj.12570","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/avj.12570","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T22:26:26Z","timestamp":1696371986000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/avj.12570"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,26]]},"references-count":22,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["10.1111\/avj.12570"],"URL":"https:\/\/doi.org\/10.1111\/avj.12570","archive":["Portico"],"relation":{},"ISSN":["0005-0423","1751-0813"],"issn-type":[{"value":"0005-0423","type":"print"},{"value":"1751-0813","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,26]]},"assertion":[{"value":"2015-04-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-07-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-04-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}