{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T00:36:16Z","timestamp":1790987776318,"version":"4.1.0"},"reference-count":29,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2017,7,27]],"date-time":"2017-07-27T00:00:00Z","timestamp":1501113600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"New Zealand International Doctoral Research Scholarship"},{"name":"Massey University Doctoral Research Scholarship"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust Veterinary J"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The aim of this research was to study the roles of the day 0 energy balance and gonadotrophin\u2010releasing hormone (<jats:styled-content style=\"fixed-case\">GnRH<\/jats:styled-content>) and progesterone levels on dominant follicle (<jats:styled-content style=\"fixed-case\">DF<\/jats:styled-content>) and corpus luteum (<jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content>) development during the first 7 days of a gonadotrophin\u2013prostaglandin\u2013gonadotrophin (<jats:styled-content style=\"fixed-case\">GPG<\/jats:styled-content>) + progesterone (<jats:styled-content style=\"fixed-case\">P4<\/jats:styled-content>) program in anoestrous dairy cows.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Cows (n = 81) were allocated to one of the three treatments: (1) GPG + <jats:styled-content style=\"fixed-case\">P4<\/jats:styled-content> (days 0 and 9, 100 \u00b5g <jats:styled-content style=\"fixed-case\">GnRH<\/jats:styled-content>; day 0\u20137, intravaginal <jats:styled-content style=\"fixed-case\">P4<\/jats:styled-content> device; day 7, 500 \u00b5g <jats:styled-content style=\"fixed-case\">PGF<jats:sub>2\u03b1<\/jats:sub><\/jats:styled-content>); (2) <jats:styled-content style=\"fixed-case\">GPG<\/jats:styled-content> (as for treatment 1 but excluding the <jats:styled-content style=\"fixed-case\">P4<\/jats:styled-content> device) and (3) prostaglandin + <jats:styled-content style=\"fixed-case\">GnRH<\/jats:styled-content> + <jats:styled-content style=\"fixed-case\">P4<\/jats:styled-content> (as for treatment 1, but excluding day 0 <jats:styled-content style=\"fixed-case\">GnRH<\/jats:styled-content>). <jats:styled-content style=\"fixed-case\">DF<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content> size, plasma concentrations of insulin, insulin\u2010like growth factor\u2010I (<jats:styled-content style=\"fixed-case\">IGF<\/jats:styled-content>\u2010I) and non\u2010esterified fatty acid (<jats:styled-content style=\"fixed-case\">NEFA<\/jats:styled-content>) were measured on days 0 and 7.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The proportion of cows with a <jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content> on day 7 was significantly different between groups (<jats:styled-content style=\"fixed-case\">GPG<\/jats:styled-content>: 78%, <jats:styled-content style=\"fixed-case\">GPG<\/jats:styled-content>+<jats:styled-content style=\"fixed-case\">P4<\/jats:styled-content>: 69%, <jats:styled-content style=\"fixed-case\">PGF<jats:sub>2\u03b1<\/jats:sub><\/jats:styled-content> + <jats:styled-content style=\"fixed-case\">GnRH<\/jats:styled-content> + <jats:styled-content style=\"fixed-case\">P4<\/jats:styled-content>: 42%, P = 0.02). The <jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content> volume on day 7 was significantly associated with treatment, treatment by time postpartum and plasma concentrations of insulin, <jats:styled-content style=\"fixed-case\">IGF<\/jats:styled-content>\u2010I and <jats:styled-content style=\"fixed-case\">NEFA<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In cows without a <jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content> present on day 0 of an oestrus synchronisation program, removal of the day 0 <jats:styled-content style=\"fixed-case\">GnRH<\/jats:styled-content> treatment led to reduced <jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content> development; however, no effect of adding progesterone was found. In contrast, in cows with a <jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content> present on day 0 inclusion of a progesterone device led to a higher <jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content> volume, but removal of the first <jats:styled-content style=\"fixed-case\">GnRH<\/jats:styled-content> injection had no effect. Response to the treatment was affected by plasma concentrations of insulin, <jats:styled-content style=\"fixed-case\">IGF<\/jats:styled-content>\u2010I and <jats:styled-content style=\"fixed-case\">NEFA<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/avj.12611","type":"journal-article","created":{"date-parts":[[2017,7,27]],"date-time":"2017-07-27T10:15:14Z","timestamp":1501150514000},"page":"281-288","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Effects of <scp>GnRH<\/scp>, a progesterone\u2010releasing device, and energy balance on an oestrus synchronisation program in anoestrous dairy cows"],"prefix":"10.1111","volume":"95","author":[{"given":"SK","family":"Sahu","sequence":"first","affiliation":[{"name":"Institute of Veterinary, Animal and Biomedical Sciences Massey University  Palmerston North New 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