{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T08:43:55Z","timestamp":1696063435111},"reference-count":16,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2017,9,13]],"date-time":"2017-09-13T00:00:00Z","timestamp":1505260800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Department of Economic Development, Jobs, Transport and Resources (DEDJTR) Victoria and SA Pathology"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust Veterinary J"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:sec><jats:title>Case report<\/jats:title><jats:p>Clinicopathological features of neuroaxonal dystrophy (NAD) in newborn, Merino\u2013Border Leicester \u00d7 Polled Dorset lambs are described. The affected lambs were unable to walk at birth and microscopic examination of brainstem and spinal cord sections revealed bilaterally symmetrical accumulations of axonal swellings (spheroids), the histological hallmark of primary NAD. The neurological deficit was also exacerbated by myelin loss and secondary axonal degeneration, particularly in the spinal cord and sciatic nerves, but also, to a more limited extent, in brainstem and spinal nerves.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Although lambs previously diagnosed with NAD have ranged in age from 2\u2009days to 7\u2009months, this is believed to be the first report of congenital NAD in this species. Moreover, the present cases are the only ones in which peripheral nerve demyelination has been found.<\/jats:p><\/jats:sec>","DOI":"10.1111\/avj.12633","type":"journal-article","created":{"date-parts":[[2017,9,13]],"date-time":"2017-09-13T11:04:52Z","timestamp":1505300692000},"page":"416-420","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Primary, congenital neuroaxonal dystrophy with peripheral nerve demyelination in Merino\u2013Border Leicester \u00d7 Polled Dorset lambs"],"prefix":"10.1111","volume":"95","author":[{"given":"MC","family":"Hawes","sequence":"first","affiliation":[{"name":"DEDJTR Victoria, Veterinary Diagnostic Services  Bundoora Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JW","family":"Finnie","sequence":"additional","affiliation":[{"name":"SA Pathology and University of Adelaide, Frome Road  Adelaide 5000 South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"IV","family":"Jerrett","sequence":"additional","affiliation":[{"name":"DEDJTR Victoria, Veterinary Diagnostic Services  Bundoora Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Badman","sequence":"additional","affiliation":[{"name":"DEDJTR Victoria, Animal Health and Welfare  Bendigo Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Scott","sequence":"additional","affiliation":[{"name":"DEDJTR Victoria, Animal Health and Welfare  Bendigo Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,9,13]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"255","volume-title":"Veterinary neuropathology","author":"Summers BA","year":"1995"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1201\/b13319-14"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-7020-5317-7.00004-7"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/avj.12222"},{"key":"e_1_2_6_6_1","volume-title":"Theory and practice of histological techniques","author":"Bancroft JD","year":"2001"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcpa.2011.09.006"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1991.tb03162.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00687690"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/00480169.1962.33475"},{"key":"e_1_2_6_11_1","first-page":"18","article-title":"New Zealand Ministry of Agriculture and Fisheries","volume":"1","author":"Animal Health Division","year":"1978","journal-title":"Surveillance"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/00480169.1988.35462"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2004.08.015"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/avj.12346"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1042\/CBI20110413"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-004-0952-x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2010.09.039"}],"container-title":["Australian Veterinary Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Favj.12633","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/avj.12633","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T11:56:43Z","timestamp":1695988603000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/avj.12633"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,13]]},"references-count":16,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1111\/avj.12633"],"URL":"https:\/\/doi.org\/10.1111\/avj.12633","archive":["Portico"],"relation":{},"ISSN":["0005-0423","1751-0813"],"issn-type":[{"value":"0005-0423","type":"print"},{"value":"1751-0813","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9,13]]},"assertion":[{"value":"2016-06-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-12-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-09-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}