{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:21:40Z","timestamp":1762507300919,"version":"3.37.3"},"reference-count":38,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,2,4]],"date-time":"2018-02-04T00:00:00Z","timestamp":1517702400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Queensland Racing Integrity Commission","award":["CT18456 G195744"],"award-info":[{"award-number":["CT18456 G195744"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust Veterinary J"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the effect of Equivac\u00ae HeV Hendra virus vaccine on Thoroughbred racing performance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Retrospective pre\u2010post intervention study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thoroughbreds with at least one start at one of six major south\u2010eastern Queensland race tracks between 1 July 2012 and 31 December 2016 and with starts in the 3\u2010month periods before and after Hendra virus vaccinations were identified. Piecewise linear mixed models compared the trends in \u2018Timeform rating\u2019 and \u2018margin to winner\u2019 before and after initial Hendra virus vaccination. Generalised linear mixed models similarly compared the odds of \u2018winning\u2019, \u2018placing\u2019 (1st\u20133rd) and \u2018winning any prize money\u2019. Timeform rating trends were also compared before and after the second and subsequent vaccinations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Analysis of data from 4208 race starts by 755 horses revealed no significant difference in performance in the 3\u2009months before versus 3\u2009months after initial Hendra vaccination for Timeform rating (P\u2009=\u20090.32), \u2018Margin to winner\u2019 (P\u2009=\u20090.45), prize money won (P\u2009=\u20090.25), wins (P\u2009=\u20090.64) or placings (P\u2009=\u20090.77). Further analysis for Timeform rating for 7844 race starts by 928 horses failed to identify any significant change in Timeform rating trends before versus after the second and subsequent vaccinations (P\u2009=\u20090.16) or any evidence of a cumulative effect for the number of vaccines received (P\u2009=\u20090.22).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>No evidence of an effect of Hendra virus vaccination on racing performance was found. The findings allow owners, trainers, industry regulators and animal health authorities to make informed decisions about vaccination.<\/jats:p><\/jats:sec>","DOI":"10.1111\/avj.12679","type":"journal-article","created":{"date-parts":[[2018,2,5]],"date-time":"2018-02-05T01:56:43Z","timestamp":1517795803000},"page":"132-141","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Investigation of the effect of Equivac\u00ae HeV Hendra virus vaccination on Thoroughbred racing performance"],"prefix":"10.1111","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1743-2833","authenticated-orcid":false,"given":"K","family":"Schemann","sequence":"first","affiliation":[{"name":"Sydney School of Veterinary Science The University of Sydney  425 Werombi Road, Camden New South Wales 2570 Australia"},{"name":"Marie Bashir Institute for Emerging Infectious Diseases The University of Sydney  Sydney NSW Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"EJ","family":"Annand","sequence":"additional","affiliation":[{"name":"Sydney School of Veterinary Science The University of Sydney  425 Werombi Road, Camden New South Wales 2570 Australia"},{"name":"Marie Bashir Institute for Emerging Infectious Diseases The University of Sydney  Sydney NSW Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"PA","family":"Reid","sequence":"additional","affiliation":[{"name":"Equine veterinary surgeon, Brisbane  Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MF","family":"Lenz","sequence":"additional","affiliation":[{"name":"Queensland Racing Integrity Commission  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"PC","family":"Thomson","sequence":"additional","affiliation":[{"name":"School of Life and Environmental Sciences The University of Sydney  Sydney NSW Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"NK","family":"Dhand","sequence":"additional","affiliation":[{"name":"Sydney School of Veterinary Science The University of Sydney  425 Werombi Road, Camden New South Wales 2570 Australia"},{"name":"Marie Bashir Institute for Emerging Infectious Diseases The University of Sydney  Sydney NSW Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,2,4]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-81-8-1927"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coviro.2016.02.004"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.7701348"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2112.151324"},{"key":"e_1_2_9_6_1","article-title":"Hendra Virus Interagency Technical Working Group","author":"Queensland Government","year":"2014","journal-title":"Hendra virus infection prevention advice."},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1712.111162"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1602.090552"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coviro.2011.10.025"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2013.06.012"},{"key":"e_1_2_9_11_1","unstructured":"Hendra virus 2017 Australian Veterinary Association"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/zph.12238"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2003.131159"},{"key":"e_1_2_9_14_1","unstructured":"NSW Government Department of Primary Industries.Hendra virus: general information on Hendra virus.2017.https:\/\/www.dpi.nsw.gov.au\/animals-and-livestock\/horses\/health-and-disease\/hendra-virus. 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