{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T18:12:51Z","timestamp":1784830371446,"version":"3.55.0"},"reference-count":41,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,3,27]],"date-time":"2019-03-27T00:00:00Z","timestamp":1553644800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust Veterinary J"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Inclusion body disease (IBD) is a disease of snakes with a global distribution and has recently been shown to be caused by reptarenaviruses. Testing for this group of viruses in asymptomatic snakes allows the association between infection and disease to be further elucidated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A reptarenavirus was detected by RT\u2010PCR in a reticulated python (<jats:italic>Malayopython reticulatus<\/jats:italic>) from an Australian zoological collection that was open\u2010mouth breathing and had erythematous oral mucosa. Another 27 pythons, 4 elapids, 2 colubrids and 2 boas from this collection were then screened. From these animals, swabs, whole blood and\/or tissue were tested for reptarenaviruses by RT\u2010PCR. Additionally, blood films from 10 snakes were examined by light microscopy for the presence of inclusion bodies. The majority of samples were collected over a 484\u2010day period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 8 animals were RT\u2010PCR\u2010positive (8\/36\u2009=\u200922.2%): 6 were pythons, 1 was a corn snake (<jats:italic>Pantherophis guttatus<\/jats:italic>) and 1 was a Madagascar tree boa (<jats:italic>Sanzinia madagascariensis<\/jats:italic>). From them, 57 samples were collected, but only one from each animal was RT\u2010PCR\u2010positive (8\/57\u2009=\u200914.0%). From all 36 animals in this study, 8\/182 samples were RT\u2010PCR\u2010positive (4.4%). Inclusion bodies were not recognised in any of the blood films. Only the reticulated python showed signs of illness, which improved without any further intervention. All other RT\u2010PCR\u2010positive snakes were apparently healthy throughout the duration of the study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study showed a weak association between the presence of reptarenaviruses and disease. Testing serially collected swab and whole\u2010blood samples increased the number of animals in which reptarenaviruses were detected.<\/jats:p><\/jats:sec>","DOI":"10.1111\/avj.12792","type":"journal-article","created":{"date-parts":[[2019,3,28]],"date-time":"2019-03-28T06:43:41Z","timestamp":1553755421000},"page":"93-102","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Reptarenaviruses in apparently healthy snakes in an Australian zoological collection"],"prefix":"10.1111","volume":"97","author":[{"given":"TH","family":"Hyndman","sequence":"first","affiliation":[{"name":"School of Veterinary Medicine Murdoch University  Murdoch Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RE","family":"Marschang","sequence":"additional","affiliation":[{"name":"Laboklin GmbH &amp; Co. KG  Bad Kissingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Bruce","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine Murdoch University  Murdoch Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Clark","sequence":"additional","affiliation":[{"name":"School of Biomedical Sciences Curtin University  Bentley WA Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SD","family":"Vitali","sequence":"additional","affiliation":[{"name":"Perth Zoo, Department of Biodiversity, Conservation and Attractions  South Perth WA Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,3,27]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jepm.2010.07.014"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.143.10.283"},{"key":"e_1_2_9_4_1","first-page":"511","article-title":"Inclusion body disease in boid snakes","volume":"25","author":"Schumacher J","year":"1994","journal-title":"J Zoo Wildl Med"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1354\/vp.37-5-449"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.2001.62.217"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.76.15.7607-7615.2002"},{"key":"e_1_2_9_8_1","first-page":"1283","volume-title":"Proceedings of the North American Veterinary Conference","author":"Garner MM","year":"2005"},{"key":"e_1_2_9_9_1","first-page":"411","article-title":"Inclusion body disease (IBD of boids): a haematological, histological and electron microscopical study","volume":"125","author":"Keilwerth M","year":"2012","journal-title":"Berl Munch Tierarztl Wochenschr"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/B0-72-169327-X\/50064-X"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.b4819"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.158.22.757"},{"key":"e_1_2_9_13_1","first-page":"15","article-title":"Inclusion body disease in a Corallus hortulanus","volume":"6","author":"Turchetti AP","year":"2013","journal-title":"Braz J Vet Pathol"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1998.tb14535.x"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/104063870101300118"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.5818\/1529-9651.13.2.18"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00180-12"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.051995-0"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01123-13"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00451-17"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02753-13"},{"key":"e_1_2_9_22_1","unstructured":"ICTV. Virus taxonomy:2017Release.https:\/\/talk.ictvonline.org\/taxonomy\/. Accessed 30 May 2018."},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01112-15"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1004900"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11262-016-1345-7"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1006881"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2012.07.030"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-1702(99)00059-3"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.15654\/TPK-140743"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2016.10.006"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1006179"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00201-12"},{"key":"e_1_2_9_33_1","first-page":"1283","volume-title":"Fields virology","author":"Buchmeier MJ","year":"2013"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0158417"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0082916"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.156.18.578"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1638\/2014-0017R1.1"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1177\/104063871102300131"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.5818\/1529-9651-24.1.11"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1201\/9781420004038.ch9"},{"key":"e_1_2_9_41_1","first-page":"30","volume-title":"Proceedings of the AAZV, AAWV, ARAV and NAZWV Joint Conference","author":"Marschang RE","year":"2001"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1177\/1040638714562825"}],"container-title":["Australian Veterinary Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Favj.12792","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/avj.12792","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/avj.12792","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/avj.12792","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T09:31:17Z","timestamp":1694338277000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/avj.12792"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,27]]},"references-count":41,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,4]]}},"alternative-id":["10.1111\/avj.12792"],"URL":"https:\/\/doi.org\/10.1111\/avj.12792","archive":["Portico"],"relation":{},"ISSN":["0005-0423","1751-0813"],"issn-type":[{"value":"0005-0423","type":"print"},{"value":"1751-0813","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,27]]},"assertion":[{"value":"2017-12-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-03-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}