{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:45:16Z","timestamp":1747183516253,"version":"3.40.5"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,12,3]],"date-time":"2019-12-03T00:00:00Z","timestamp":1575331200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust Veterinary J"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Bone sarcomas are a significant cause of pain, disability, and mortality in dogs. A variety of surgical limb salvage options are available to preserve limb function with comparable prognosis to amputation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Report<\/jats:title><jats:p>This report describes successful healing after plate fixation of an undifferentiated sarcoma pathologic femoral fracture in a dog. The fracture was treated surgically with curettage of the tumour site, placement of autogenous bone graft, and then stabilized using a locking plate rod construct. The patient regained excellent mobility after surgery and was managed with monthly pamidronate therapy. Serial radiographs demonstrate progressive healing of the pathologic fracture. Ultimately, the patient developed a maxillary fibrosarcoma and was euthanased 1 year after treatment of the femoral fracture. Postmortem histopathological evaluation of the pathologic fracture site demonstrated complete bone healing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This case highlights the possibilities of limb salvage by fracture stabilization and bone healing as a viable option in select patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/avj.12899","type":"journal-article","created":{"date-parts":[[2019,12,3]],"date-time":"2019-12-03T08:39:40Z","timestamp":1575362380000},"page":"84-89","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pathologic fracture healing after femoral limb salvage in a dog"],"prefix":"10.1111","volume":"98","author":[{"given":"MA","family":"Hayes","sequence":"first","affiliation":[{"name":"Department of Surgical Sciences School of Veterinary Medicine, University of Wisconsin  Madison Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Jemilo","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences School of Veterinary Medicine, University of Wisconsin  Madison Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0028-6005","authenticated-orcid":false,"given":"P","family":"Muir","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences School of Veterinary Medicine, University of Wisconsin  Madison Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Sullivan","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences School of Veterinary Medicine, University of Wisconsin  Madison Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2987-7722","authenticated-orcid":false,"given":"JA","family":"Bleedorn","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences School of Veterinary Medicine, University of Wisconsin  Madison Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,12,3]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/1746-6148-8-56"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.232.10.1504"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.5326\/0450033"},{"key":"e_1_2_8_5_1","first-page":"1734","article-title":"Limb\u2010sparing treatment for osteosarcoma in dogs","volume":"195","author":"LaRue SM","year":"1989","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2006.00185.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2014.12082.x"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2012.00968.x"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/vco.12040"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2008.0221.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2007.tb02986.x"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2011.00811.x"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2011.00820.x"},{"key":"e_1_2_8_14_1","first-page":"98","article-title":"Repair of three pathologic fractures in a dog with multiple myeloma","volume":"33","author":"Banks T","year":"2003","journal-title":"Aust Vet Pract"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminoncol.2007.11.019"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00590-016-1857-9"},{"key":"e_1_2_8_17_1","first-page":"650","article-title":"Transtumoral plating as a novel method for palliative limb spare and thromboembolism in a dog with a distal radial primary bone tumor","volume":"52","author":"Boston SE","year":"2011","journal-title":"Can Vet J"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-198309000-00041"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2009.00596.x"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5849.341"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.12151"},{"key":"e_1_2_8_22_1","first-page":"3266","article-title":"Two competing influences that may explain concomitant tumor resistance","volume":"52","author":"Prehn RT","year":"1993","journal-title":"Cancer Res"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.90B9.20671"}],"container-title":["Australian Veterinary Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/avj.12899","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/avj.12899","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/avj.12899","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T07:39:59Z","timestamp":1694072399000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/avj.12899"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,3]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["10.1111\/avj.12899"],"URL":"https:\/\/doi.org\/10.1111\/avj.12899","archive":["Portico"],"relation":{},"ISSN":["0005-0423","1751-0813"],"issn-type":[{"type":"print","value":"0005-0423"},{"type":"electronic","value":"1751-0813"}],"subject":[],"published":{"date-parts":[[2019,12,3]]},"assertion":[{"value":"2019-08-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-12-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}