{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T10:35:59Z","timestamp":1788863759263,"version":"build-2803163510"},"reference-count":46,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2020,6,24]],"date-time":"2020-06-24T00:00:00Z","timestamp":1592956800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust Veterinary J"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Review medical records of dogs that underwent adrenalectomy without pre\u2010operative medical management, to examine the peri\u2010operative morbidity and mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Case series of 65 dogs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Medical records were reviewed. Features recorded included the histologic diagnosis, intra\u2010operative hypertension or tachycardia, requirement for cavotomy, administration of intra\u2010 and post\u2010operative corticosteroids, performance of additional surgery and the occurrence of peri\u2010operative complications. Dogs requiring emergency surgery were excluded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 65 dogs, 49 had adrenocortical tumours (11 bilateral), 13 had pheochromocytomas (one bilateral) and three dogs had tumours in both adrenal glands of a different tumour type. Five dogs had caudal vena cava invasion and 33 had additional procedures performed at the same time. Mortality occurred in 1\/65 dogs (1.5%; 95% CI 0.03%\u20138.2%), major complications were identified in 1\/65 dogs (1.5%; 95% CI 0.03%\u20138.2%) and minor complications occurred in 10\/53 dogs (15%; 95% CI 8.6%\u201326%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Based on the limited peri\u2010operative complications and low mortality in this pre\u2010operatively untreated cohort, and based on critique of the available literature, the added value afforded by pre\u2010operative treatment is questioned. With appropriate management, adrenal tumours can be removed with few peri\u2010operative complications and low mortality.<\/jats:p><\/jats:sec>","DOI":"10.1111\/avj.12991","type":"journal-article","created":{"date-parts":[[2020,6,25]],"date-time":"2020-06-25T03:19:45Z","timestamp":1593055185000},"page":"449-454","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Short\u2010term outcome of adrenalectomy in dogs with adrenal gland tumours that did not receive pre\u2010operative medical management"],"prefix":"10.1111","volume":"98","author":[{"given":"C","family":"Appelgrein","sequence":"first","affiliation":[{"name":"School of Veterinary Medicine Murdoch University Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Hosgood","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine Murdoch University Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Drynan","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine Murdoch University Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Nesbitt","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine Murdoch University Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,6,24]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"504","volume-title":"Withrow and MacEwan's small animal clinical oncology","author":"Lunn KL","year":"2007"},{"key":"e_1_2_8_3_1","first-page":"1360","article-title":"Results of surgical treatment for hyperadrenocorticism caused by adrenocortical neoplasia in the dog 25 cases","volume":"189","author":"Scavelli TD","year":"1986","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.1997.tb00464.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.5326\/15473317-37-1-93"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2003.223.654"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.5326\/JAAHA-MS-5669"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.242.12.1715"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2001.219.1725"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.153.17.521"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2005.226.1662"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2005.226.556"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1354\/vp.42-1-52"},{"key":"e_1_2_8_14_1","first-page":"2033","volume-title":"Veterinary surgery: Small animal","author":"Adin CA","year":"2012"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.150.26.799"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.2003.tb12498.x"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.161.24.805"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/vec.12801"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2008.0182.x"},{"key":"e_1_2_8_20_1","volume-title":"Plumb's veterinary drug handbook","author":"Plumb DC","year":"2011"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.1995.tb00231.x"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-016-0895-1"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(97)50029-5"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.12462"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.232.1.77"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.12159"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.12005"},{"key":"e_1_2_8_28_1","first-page":"E3","article-title":"Hypercoagulability in dogs: Pathophysiology","volume":"34","author":"Kitrell D","year":"2012","journal-title":"Compend Contin Educ Vet"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.12162"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-165X.2009.00161.x"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.238.4.463"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11845-015-1383-5"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.12569"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000539-200011000-00013"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-11-0162"},{"key":"e_1_2_8_36_1","first-page":"1","article-title":"Management of life\u2010threatening hypertension in a 12\u2010year\u2010old bichon frise undergoing an adrenalectomy for phaeochromocytoma excision","volume":"4","author":"Ferreira JP","year":"2016","journal-title":"Vet Rec Case Reports"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.12552"},{"key":"e_1_2_8_38_1","first-page":"163","volume-title":"Canine and feline anaesthesia and co\u2010existing disease","author":"Fischer B","year":"2015"},{"key":"e_1_2_8_39_1","first-page":"651","volume-title":"Lumb and Jones' veterinary anaesthesia","author":"Adams J","year":"2015"},{"key":"e_1_2_8_40_1","first-page":"250","volume-title":"Lumb and Jones' veterinary anaesthesia","author":"Pang D","year":"2015"},{"key":"e_1_2_8_41_1","first-page":"373","volume-title":"Clinical Anesthesiology","author":"Morgan G","year":"2006"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.4314\/ovj.v6i1.9"},{"key":"e_1_2_8_43_1","doi-asserted-by":"crossref","first-page":"322","DOI":"10.2460\/javma.1997.211.03.322","article-title":"Comparison of results of adrenocorticotropic hormone stimulation and low\u2010dose dexamethasone suppression tests with necropsy findings in dogs: 81 cases (1985\u20131995)","volume":"211","author":"Van Liew CH","year":"1997","journal-title":"J Am Vet Med Assoc"},{"issue":"2","key":"e_1_2_8_44_1","first-page":"239","article-title":"Adrenalectomy in dogs with adrenal gland tumors: 52 cases (2002\u20132008)","author":"Massari F","year":"2011","journal-title":"Journal of the American Veterinary Medical Association."},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2006.00164.x"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2009.01593.x"},{"key":"e_1_2_8_47_1","first-page":"517","volume-title":"Small Animal Clinical Pharmacology","author":"Church D"}],"container-title":["Australian Veterinary Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Favj.12991","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/avj.12991","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/avj.12991","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/avj.12991","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T10:44:11Z","timestamp":1723113851000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/avj.12991"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,24]]},"references-count":46,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["10.1111\/avj.12991"],"URL":"https:\/\/doi.org\/10.1111\/avj.12991","archive":["Portico"],"relation":{},"ISSN":["0005-0423","1751-0813"],"issn-type":[{"value":"0005-0423","type":"print"},{"value":"1751-0813","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,24]]},"assertion":[{"value":"2020-03-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}