{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T13:27:25Z","timestamp":1760016445047},"reference-count":23,"publisher":"Wiley","issue":"1-2","license":[{"start":{"date-parts":[[2020,10,6]],"date-time":"2020-10-06T00:00:00Z","timestamp":1601942400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust Veterinary J"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec><jats:title>Case report<\/jats:title><jats:p>This case report describes the clinical signs and case management of a 1\u2010year\u2010old neutered male Siberian Husky that accidentally ingested 635\u2009mg\/kg of oral acetazolamide (a carbonic anhydrase inhibitor). The dog presented with severe tachypnoea due to the development of hyperchloraemic metabolic acidosis and associated hypokalaemia that persisted for 7\u2009days. Clinical and biochemical changes resolved with intravenous and subsequent oral supplementation of sodium bicarbonate and potassium. Complete recovery occurred within 9\u2009days of presentation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>To the authors' knowledge, this is the first case that reports overdosage of an oral carbonic anhydrase inhibitor in a dog and subsequent recovery with adequate supplementation and supportive care.<\/jats:p><\/jats:sec>","DOI":"10.1111\/avj.13027","type":"journal-article","created":{"date-parts":[[2020,10,7]],"date-time":"2020-10-07T05:03:58Z","timestamp":1602047038000},"page":"11-14","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Severe metabolic acidosis due to acetazolamide intoxication in a dog"],"prefix":"10.1111","volume":"99","author":[{"given":"L","family":"Johnston","sequence":"first","affiliation":[{"name":"Internal Medicine Veterinary Specialist Services  Eastlake Street Carrara Queensland 4211 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