{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T13:53:26Z","timestamp":1772891606340,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,1,13]],"date-time":"2021-01-13T00:00:00Z","timestamp":1610496000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust Veterinary J"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Brain metastases are well known for disseminated hemangiosarcoma involving the right atrium\/auricle.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case report<\/jats:title><jats:p>An 8\u2010year\u2010old male Australian Shepherd Dog presented with a 3\u2010day history of circling to the left. A neurological examination revealed obtunded mentation, right hemi\u2010inattention, bilateral strabismus towards the left side and absent physiological nystagmus. In addition, the dog had muffled heart sounds on auscultation and exercise\u2010induced weakness. Laboratory findings included hypercoagulability and marked elevation in the C\u2010reactive protein concentration. Electrocardiography detected a sinus rhythm with right bundle\u2010branch block and ventricular bigeminy. Echocardiography revealed an extensive interventricular septal mass. Due to the grave prognosis, the owners elected for euthanasia, and a complete necropsy was performed. The main pathological findings were an interventricular septal and left ventricular hemangiosarcoma, with metastases in the brain, lungs, spleen and adrenal glands. No evidence of tumour infiltration was found in the right atrium.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>To the authors' knowledge, this is the first report of neurological signs due to confirmed brain metastases in a dog with interventricular septal hemangiosarcoma. Although the right atrium is the main location for cardiac hemangiosarcoma, the interventricular septum should be evaluated in all cases.<\/jats:p><\/jats:sec>","DOI":"10.1111\/avj.13050","type":"journal-article","created":{"date-parts":[[2021,1,15]],"date-time":"2021-01-15T18:35:14Z","timestamp":1610735714000},"page":"119-123","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["A neurological presentation caused by brain metastases in a dog with interventricular septal hemangiosarcoma"],"prefix":"10.1111","volume":"99","author":[{"given":"TA","family":"Bunn","sequence":"first","affiliation":[{"name":"School of Veterinary Medicine Murdoch University Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2264-307X","authenticated-orcid":false,"given":"C","family":"Robveille","sequence":"additional","affiliation":[{"name":"School of Veterinary 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