{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T04:10:55Z","timestamp":1776831055021,"version":"3.51.2"},"reference-count":15,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,3,8]],"date-time":"2022-03-08T00:00:00Z","timestamp":1646697600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust Veterinary J"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Neoplasia is considered to be rare in macropods. Anaplastic thyroid carcinoma (ATC) also known as undifferentiated or giant cell carcinoma, is a rare but aggressive and lethal solid tumour reported to affect humans, dogs, cats, racoons and birds. It is derived from poorly differentiated follicular cells and lacks the characteristic architectural pattern of arrangement of tumour cells. ATC has not previously been reported in macropods.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Report<\/jats:title><jats:p>A brush\u2010tailed rock\u2010wallaby (<jats:italic>Petrogale penicillata<\/jats:italic>) was presented for a mass on the ventral neck. A clinical diagnosis of thyroid carcinoma was suspected based on radiology, ultrasound and cytology. Other than palliative care, treatment was declined. Four months later the wallaby was found dead and submitted for necropsy. Gross examination and histopathology demonstrated a unilateral ATC with vascular neoplastic emboli and distant metastases to the heart, lungs and liver.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The clinical signs associated with thyroid tumours may be the result of localised growth and expansion of the thyroid, metastatic disease or a combination of these effects. Most thyroid tumours are nonfunctional. Based on the lack of typical clinical signs associated with functional thyroid tumours, in this case, we conclude that the thyroid tumour in this wallaby was likely to be nonfunctional. The cause of death in this wallaby was likely due to the heavy tumour burden with compromised cardiorespiratory function exacerbated by dorsoventral compression of the larynx. More study is needed to better understand thyroid neoplasia in macropods.<\/jats:p><\/jats:sec>","DOI":"10.1111\/avj.13157","type":"journal-article","created":{"date-parts":[[2022,3,8]],"date-time":"2022-03-08T08:24:31Z","timestamp":1646727871000},"page":"271-276","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Anaplastic thyroid carcinoma in a <scp>brush\u2010tailed<\/scp> rock\u2010wallaby (<i>Petrogale penicillata<\/i>)"],"prefix":"10.1111","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7623-3204","authenticated-orcid":false,"given":"RJT","family":"Doneley","sequence":"first","affiliation":[{"name":"School of Veterinary Science The University of Queensland  Gatton Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"WW","family":"Suen","sequence":"additional","affiliation":[{"name":"Australian Centre for Disease Preparedness (ACDP), Commonwealth Scientific and Industrial Research Organisation (CSIRO)  East Geelong Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,3,8]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"KesslerM.Surgery in thyroid disease.Proceedings of the annual conference of the World Small Animal Veterinary Association 2014. 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Accessed 13 March 2020."},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-7020-5319-1.00014-1"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/PCR.0000000000000107"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12565-015-0293-y"},{"key":"e_1_2_6_16_1","volume-title":"Fauna of Australia volume 1b Mammalia","author":"Dawson TJ"}],"container-title":["Australian Veterinary Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/avj.13157","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/avj.13157","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/avj.13157","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T06:56:10Z","timestamp":1692946570000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/avj.13157"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,8]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["10.1111\/avj.13157"],"URL":"https:\/\/doi.org\/10.1111\/avj.13157","archive":["Portico"],"relation":{},"ISSN":["0005-0423","1751-0813"],"issn-type":[{"value":"0005-0423","type":"print"},{"value":"1751-0813","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,8]]},"assertion":[{"value":"2021-12-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}