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Although<jats:italic>B. suis<\/jats:italic>infection in dogs shares some clinical similarities to the host\u2010adapted species (<jats:italic>B. canis<\/jats:italic>),<jats:italic>B. suis<\/jats:italic>remains an incompletely understood pathogen in dogs with limited published data on its pathogenesis and clinical features. This case series describes the presentations, diagnosis, and clinical management of<jats:italic>B. suis<\/jats:italic>infection in three dogs: (1) a bitch with dystocia, abortion and mastitis; (2) an entire male dog with septic arthritis and presumptive osteomyelitis; and (3) a castrated male dog with lymphadenitis. Unique features of these cases are reported including the first documented detection of<jats:italic>B. suis<\/jats:italic>from milk and isolation from lymph nodes of canine patients, as well as the follow\u2010up of pups born to a<jats:italic>B. suis<\/jats:italic>\u2010infected bitch. Consistent with previous reports, all three dogs showed a favourable clinical response to combination antibiotic therapy with rifampicin and doxycycline. Individually tailored drug regimens were required based on the clinical presentation and other factors, including owner expectations and compliance with therapy as well as a zoonotic risk assessment (generally considered low, except around time of whelping). The authors include their recommendations for the clinical management of dogs that are at\u2010risk or seropositive for<jats:italic>B. suis<\/jats:italic>with or without clinical signs or laboratory\u2010confirmed infection.<\/jats:p>","DOI":"10.1111\/avj.13227","type":"journal-article","created":{"date-parts":[[2023,1,19]],"date-time":"2023-01-19T09:29:10Z","timestamp":1674120550000},"page":"133-141","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["<i>Brucella suis<\/i>in three dogs: presentation, diagnosis and clinical management"],"prefix":"10.1111","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9201-3631","authenticated-orcid":false,"given":"CC","family":"Kneipp","sequence":"first","affiliation":[{"name":"Faculty of Veterinary and Agricultural Sciences The University of Melbourne Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AM","family":"Rose","sequence":"additional","affiliation":[{"name":"School of Veterinary Science The University of Queensland Gatton Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Robson","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Molecular Pathology Sullivan Nicolaides Pathology Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Malik","sequence":"additional","affiliation":[{"name":"Centre for Veterinary Education University of Sydney Sydney New South Wales Australia"},{"name":"School of Animal and Veterinary Sciences Albert Pugsley Pl, Charles Sturt University New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AT","family":"Deutscher","sequence":"additional","affiliation":[{"name":"Elizabeth MacArthur Agricultural Institute NSW Department Primary Industries Menangle New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7872-934X","authenticated-orcid":false,"given":"AK","family":"Wiethoelter","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary and Agricultural Sciences The University of Melbourne Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0121-2016","authenticated-orcid":false,"given":"SM","family":"Mor","sequence":"additional","affiliation":[{"name":"Institute of Infection, Veterinary and Ecological Sciences The University of Liverpool Liverpool UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,1,19]]},"reference":[{"key":"e_1_2_5_2_1","unstructured":"QLD Government Department of Agriculture and Fisheries.Brucellosis.https:\/\/www.daf.qld.gov.au\/business-priorities\/biosecurity\/animal-biosecurity-welfare\/animal-health-pests-diseases\/notifiable. 2018. 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