{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T04:28:17Z","timestamp":1759638497568,"version":"3.40.5"},"reference-count":15,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,5,9]],"date-time":"2023-05-09T00:00:00Z","timestamp":1683590400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust Veterinary J"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:p>Anthelmintic resistance (AR) is a well\u2010recognized challenge in farmed ruminants. The use of anthelmintics in combination is one of the strategies recommended to slow the rate of AR development. Two studies were undertaken in 2017 and 2019 to assess the efficacy of single\u2010dose macrocyclic lactone (ML) anthelmintic and ML combination drenches. In total, 11 Faecal Egg Count Reduction Trials (FECRTs) were set up in 10 different beef herds, with results available from 10 of those FECRTs (9 herds). AR to a single ML anthelmintic was detected in all 9 herds, with resistance to <jats:italic>Cooperia<\/jats:italic> and <jats:italic>Haemonchus<\/jats:italic> spp on 9 farms, and resistance to <jats:italic>Ostertagia<\/jats:italic> and <jats:italic>Trichostrongylus<\/jats:italic> spp on 2 farms. In contrast, for the ML combination anthelmintics, all FECRTs resulted in efficacies of 99%\u2013100%. The results suggest that cattle producers should strongly consider using combination drenches in their herds in preference to single actives.<\/jats:p>","DOI":"10.1111\/avj.13248","type":"journal-article","created":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T17:13:47Z","timestamp":1683738827000},"page":"293-295","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Comparison of the efficacy of macrocyclic lactone anthelmintics, either singly or in combination with other anthelmintic(s), in nine beef herds in southern <scp>NSW<\/scp>"],"prefix":"10.1111","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1185-3167","authenticated-orcid":false,"given":"MB","family":"Allworth","sequence":"first","affiliation":[{"name":"Fred Morley Centre Charles Sturt University  Wagga Wagga New South Wales 2678 Australia"},{"name":"School of Agricultural, Environmental and Veterinary Sciences Charles Sturt University  Wagga Wagga New South Wales 2678 Australia"},{"name":"Gulbali institute Charles Sturt University  Wagga Wagga New South Wales 2678 Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Goonan","sequence":"additional","affiliation":[{"name":"School of Agricultural, Environmental and Veterinary Sciences Charles Sturt University  Wagga Wagga New South Wales 2678 Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JE","family":"Nelson","sequence":"additional","affiliation":[{"name":"School of Agricultural, Environmental and Veterinary Sciences Charles Sturt University  Wagga Wagga New South Wales 2678 Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Kelly","sequence":"additional","affiliation":[{"name":"Boehringer Ingelheim Animal Health Australia Pty. 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