{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T12:32:40Z","timestamp":1777984360184,"version":"3.51.4"},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,3,18]],"date-time":"2019-03-18T00:00:00Z","timestamp":1552867200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100004331","name":"Johnson and Johnson","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004331","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brit J Clinical Pharma"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:p>Temporal patterns of acetaminophen use exceeding the recommended daily maximum dosage of 4\u00a0g over a 5\u2010year period (4\/1\/2011\u20133\/31\/2016) were evaluated in an online 1\u2010week diary study of 14\u00a0434 adult acetaminophen users who also reported acetaminophen use in the previous month. Specific medications taken were identified by list\u2010based prompting; respondents were not required to know their medications contained acetaminophen. Details of use were recorded daily; total daily dosage was determined programmatically. Prevalence of &gt;4\u00a0g use over time was modelled and tested for linear changes. The overall prevalence of &gt;4\u00a0g use (6.3% of users and 3.7% of usage days) did not change over the 5 years: odds ratio (OR) persons, 1.02 (95% CI, 0.98\u20131.09); OR days, 0.98 (0.92\u20131.05). Deviations from label directions were largely unchanged, though concomitant use increased slightly. Thus, over a recent 5\u2010year period, there was no evidence of change in how often acetaminophen use exceeded the labelled maximum daily dose.<\/jats:p>","DOI":"10.1111\/bcp.13894","type":"journal-article","created":{"date-parts":[[2019,2,11]],"date-time":"2019-02-11T05:48:42Z","timestamp":1549864122000},"page":"1028-1034","source":"Crossref","is-referenced-by-count":4,"title":["Five\u2010year trends in acetaminophen use exceeding the recommended daily maximum dose"],"prefix":"10.1111","volume":"85","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2150-5070","authenticated-orcid":false,"given":"David W.","family":"Kaufman","sequence":"first","affiliation":[{"name":"Slone Epidemiology Center at Boston University  Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith P.","family":"Kelly","sequence":"additional","affiliation":[{"name":"Slone Epidemiology Center at Boston University  Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deena R.","family":"Battista","sequence":"additional","affiliation":[{"name":"Pinney Associates  Pittsburgh PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary K.","family":"Malone","sequence":"additional","affiliation":[{"name":"Appleseed Consumer Insight  Arlington MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel B.","family":"Weinstein","sequence":"additional","affiliation":[{"name":"Janssen Research &amp; Development, LLC  Titusville NJ USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9639-490X","authenticated-orcid":false,"given":"Saul","family":"Shiffman","sequence":"additional","affiliation":[{"name":"Pinney Associates  Pittsburgh PA USA"},{"name":"Department of Psychology University of Pittsburgh  Pittsburgh PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,3,18]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.3.337"},{"key":"e_1_2_9_3_1","unstructured":"Patterns of medication use in the United States 2006: A report from the Slone survey. 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