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Among the many symptoms of COVID\u201019, fever and diffuse pain predominant and therefore it can be assumed that metamizole may be widely used in the current epidemic period. So far, there have been no reports on the safety of metamizole in COVID\u201019 patients. We describe a series of 3 patients who developed severe neutropenia under metamizole treatment, raising a concern of a possible increased risk of this side effect among COVID\u201019 patients.<\/jats:p>","DOI":"10.1111\/bcp.14703","type":"journal-article","created":{"date-parts":[[2020,12,18]],"date-time":"2020-12-18T11:16:49Z","timestamp":1608290209000},"page":"2902-2906","source":"Crossref","is-referenced-by-count":7,"title":["A possible increased risk of metamizole\u2010associated neutropenia among COVID\u201019 patients"],"prefix":"10.1111","volume":"87","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2491-9930","authenticated-orcid":false,"given":"Tsahi T.","family":"Lerman","sequence":"first","affiliation":[{"name":"Department of Internal Medicine F\u2010Recanati Rabin Medical Center, Beilinson Hospital  Petah Tiqva Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University  Ramat Aviv, Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moshe","family":"Sagi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine F\u2010Recanati Rabin Medical Center, Beilinson Hospital  Petah Tiqva Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University  Ramat Aviv, Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yair","family":"Shafir","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine F\u2010Recanati Rabin Medical Center, Beilinson Hospital  Petah Tiqva Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University  Ramat Aviv, Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liron","family":"Sheena","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine F\u2010Recanati Rabin Medical Center, Beilinson Hospital  Petah Tiqva Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University  Ramat Aviv, Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eytan","family":"Cohen","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine F\u2010Recanati Rabin Medical Center, Beilinson Hospital  Petah Tiqva Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University  Ramat Aviv, Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elad","family":"Goldberg","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine F\u2010Recanati Rabin Medical Center, Beilinson Hospital  Petah Tiqva Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University  Ramat Aviv, Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilan","family":"Krause","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine F\u2010Recanati Rabin Medical Center, Beilinson Hospital  Petah Tiqva Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University  Ramat Aviv, Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,1,7]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"CD011421","article-title":"Single dose dipyrone (metamizole) for acute postoperative pain in adults","volume":"4","author":"Hearn L","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_9_3_1","article-title":"Single dose dipyrone for acute renal colic pain","volume":"21","author":"Edwards J","year":"2002","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.06-8061com"},{"key":"e_1_2_9_5_1","unstructured":"WITHDRAWN: a resource for withdrawn and discontinued drugs. 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