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Patients who were delabelled were contacted by phone after 6\u00a0months to determine outcomes after any therapeutic penicillin\u2010class antibiotic intake.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 39 patients were evaluated and 33 (84.6%) were delabelled. Five patients were penicillin skin\u2010test positive and one was oral challenge positive. We succeeded in contacting 33 delabelled patients at 6\u00a0months. Twenty\u2010two patients tolerated a subsequent therapeutic course of amoxicillin, eight patients did not retake penicillin due to a lack of therapeutic indication, and three patients refused an indicated penicillin use fearful of another reaction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study highlights the importance of allergy work\u2010up in the diagnosis of beta\u2010lactam hypersensitivity. Most patients were excessively labelled as beta\u2010lactam allergic and this mislabelling could increase healthcare costs and lead to the development of drug resistance by the use of wide\u2010spectrum antibiotics<\/jats:p><\/jats:sec>","DOI":"10.1111\/bcp.14879","type":"journal-article","created":{"date-parts":[[2021,4,26]],"date-time":"2021-04-26T06:39:16Z","timestamp":1619419156000},"page":"4619-4624","source":"Crossref","is-referenced-by-count":7,"title":["Betalactam hypersensitivity: The importance of delabelling in primary care"],"prefix":"10.1111","volume":"87","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9558-0666","authenticated-orcid":false,"given":"Najah","family":"Ben Fadhel","sequence":"first","affiliation":[{"name":"Department of Pharmacology University Hospital of Fattouma Bourguiba Monastir  Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fares","family":"Aroua","sequence":"additional","affiliation":[{"name":"Department of Pharmacology 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