{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T07:51:14Z","timestamp":1790495474318,"version":"4.1.0"},"reference-count":41,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,9,2]],"date-time":"2021-09-02T00:00:00Z","timestamp":1630540800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004047","name":"Karolinska Institutet","doi-asserted-by":"publisher","award":["2009Fobi0762"],"award-info":[{"award-number":["2009Fobi0762"]}],"id":[{"id":"10.13039\/501100004047","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004047","name":"Karolinska Institutet","doi-asserted-by":"publisher","award":["2018\u201001516"],"award-info":[{"award-number":["2018\u201001516"]}],"id":[{"id":"10.13039\/501100004047","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brit J Clinical Pharma"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Psychotropic drugs like opioids and benzodiazepines are prescribed for traumas resulting from road traffic crashes and the risk of developing an addiction deserves consideration. This study aims to shed light on how the consumption of those drugs evolves over time among older road traffic injury (RTI) victims.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a nationwide Swedish register\u2010based longitudinal study to identify trajectories of post\u2010RTI psychotropic drug use. All individuals aged 50\u2009years and older who had a hospital visit for an RTI from 2007 to 2015 were followed up during a 2\u2010year period; those who used the drugs prior to the RTI were excluded. Trajectories were identified by performing latent class trajectory analysis on drug dispensation data for opioids and benzodiazepines separately (66\u2009034 and 66\u2009859 adults, respectively, in total).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three trajectories were identified for opioids and four for benzodiazepines. The largest group in both instances included people with no\u2010use\/minimal use throughout the follow\u2010up (81.3% and 92.8%). \u201cSporadic users\u201d were more frequent among users of opioids (16.7%) than benzodiazepines (4.3%), whereas \u201cchronic users\u201d were found in similar proportions (2.0% and 1.8%). \u201cDelayed chronic use\u201d characterized the fourth group of benzodiazepine users (1.0%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Several trajectories of psychotropic drug use were identified after RTI, from limited to chronic. Although chronic use was uncommon, a better understanding of the factors likely to increase that risk is warranted given the seriousness of the problem.<\/jats:p><\/jats:sec>","DOI":"10.1111\/bcp.15019","type":"journal-article","created":{"date-parts":[[2021,7,31]],"date-time":"2021-07-31T14:05:53Z","timestamp":1627740353000},"page":"764-772","source":"Crossref","is-referenced-by-count":5,"title":["Post\u2010injury benzodiazepine and opioid use among older adults involved in road traffic crashes: A Swedish register\u2010based longitudinal study"],"prefix":"10.1111","volume":"88","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3310-4178","authenticated-orcid":false,"given":"Jeanne","family":"Duchesne","sequence":"first","affiliation":[{"name":"Department of Global Public Health Karolinska Institutet  Stockholm Sweden"},{"name":"Institut de Sant\u00e9 Publique, d'Epid\u00e9miologie et de D\u00e9veloppement Universit\u00e9 de Bordeaux  Bordeaux France"},{"name":"Team IETO, Bordeaux 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