{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T14:57:13Z","timestamp":1778943433339,"version":"3.51.4"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,4,27]],"date-time":"2022-04-27T00:00:00Z","timestamp":1651017600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brit J Clinical Pharma"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:p>Erythema nodosum (EN), the most common form of panniculitis, is a reactive inflammation of the subcutaneous fat clinically presented with a sudden onset of painful, erythematous, nodular, subcutaneous lesions, typically localized to the pretibial area. EN is commonly caused by numerous infections (especially beta\u2010haemolytic streptococcal infections), autoimmune diseases (sarcoidosis), inflammatory bowel conditions and drugs. EN induced by Covid\u201019 vaccines is rarely reported. We describe an original clinical observation of a 75\u2010year\u2010old woman who presented with EN after receiving the second dose of BNT162b2, an mRNA vaccine.<\/jats:p>","DOI":"10.1111\/bcp.15351","type":"journal-article","created":{"date-parts":[[2022,4,18]],"date-time":"2022-04-18T02:29:36Z","timestamp":1650248976000},"page":"536-540","source":"Crossref","is-referenced-by-count":6,"title":["Erythema nodosum induced by Covid\u201019 Pfizer\u2010BioNTech mRNA vaccine: A case report and brief literature review"],"prefix":"10.1111","volume":"89","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0041-2921","authenticated-orcid":false,"given":"Ferdaous","family":"Chahed","sequence":"first","affiliation":[{"name":"Department of Clinical Pharmacology University Hospital of Monastir. University of Monastir  Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9558-0666","authenticated-orcid":false,"given":"Najah","family":"Ben Fadhel","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology University Hospital of Monastir. University of Monastir  Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5755-5117","authenticated-orcid":false,"given":"Haifa","family":"Ben Romdhane","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology University Hospital of Monastir. University of Monastir  Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monia","family":"Youssef","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital of Monastir. University of Monastir  Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9675-1356","authenticated-orcid":false,"given":"Seifeddine","family":"Ben Hammouda","sequence":"additional","affiliation":[{"name":"Department of Pathology University Hospital of Monastir. University of Monastir  Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9703-1943","authenticated-orcid":false,"given":"Amel","family":"Chaabane","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology University Hospital of Monastir. University of Monastir  Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5828-8076","authenticated-orcid":false,"given":"Karim","family":"Aouam","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology University Hospital of Monastir. University of Monastir  Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4820-4312","authenticated-orcid":false,"given":"Nadia","family":"Ben Fredj","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology University Hospital of Monastir. University of Monastir  Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,4,27]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2008.05.014"},{"issue":"5","key":"e_1_2_7_3_1","first-page":"695","article-title":"Erythema nodosum: A sign of systemic disease","volume":"75","author":"Schwartz RA","year":"2007","journal-title":"Am Fam Physician"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365540410027184"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12519\u2010018\u20100191\u20101"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13555\u2010013\u20100035\u20109"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0234025"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2020.12.047"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17678"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.19529"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdin.2021.12.009"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17762"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1981.154"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529\u20108019.2010.01332.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2017.00233"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.5070\/D34vw9v3cs"},{"issue":"5","key":"e_1_2_7_17_1","first-page":"437","article-title":"Erythema nodosum and hepatitis B: a case report and literature review","volume":"41","author":"Wu Y\u2010L","year":"2008","journal-title":"J Microbiol Immunol Infect"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10225344"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2021.03.092"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.20639"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.14104"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdcr.2021.07.038"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17268"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2021.06.026"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17578"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17582"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17576"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines9111313"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1980.01640290067014"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2020-236613"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines9050435"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.15548"}],"container-title":["British Journal of Clinical Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bcp.15351","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/bcp.15351","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bpspubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bcp.15351","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T08:45:36Z","timestamp":1692521136000},"score":1,"resource":{"primary":{"URL":"https:\/\/bpspubs.onlinelibrary.wiley.com\/doi\/10.1111\/bcp.15351"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,27]]},"references-count":31,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["10.1111\/bcp.15351"],"URL":"https:\/\/doi.org\/10.1111\/bcp.15351","archive":["Portico"],"relation":{},"ISSN":["0306-5251","1365-2125"],"issn-type":[{"value":"0306-5251","type":"print"},{"value":"1365-2125","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,27]]}}}