{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T08:57:50Z","timestamp":1777539470820,"version":"3.51.4"},"reference-count":11,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,3,9]],"date-time":"2015-03-09T00:00:00Z","timestamp":1425859200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Basic Clin Pharma Tox"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The post\u2010injection olanzapine delirium\/sedation syndrome (<jats:styled-content style=\"fixed-case\">PDSS<\/jats:styled-content>) was observed in a 60\u2010year\u2010old Caucasian, schizophrenic, non\u2010smoker and underweight [body mass index (<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>), 18.2\u00a0kg\/m<jats:sup>2<\/jats:sup>] women after the fourth intramuscular injection of 405\u00a0mg olanzapine pamoate. Clinical symptoms of <jats:styled-content style=\"fixed-case\">PDSS<\/jats:styled-content> were similar to those of acute oral olanzapine intoxication. The patient received supportive treatment and recovered fully. High olanzapine concentrations in serum, with maximum level of 698\u00a0ng\/mL, were confirmed by liquid chromatography with tandem mass spectrometry (<jats:styled-content style=\"fixed-case\">LC<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">MS<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">MS<\/jats:styled-content>). The authors wonder whether a low <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> and advanced age may predispose patients to <jats:styled-content style=\"fixed-case\">PDSS<\/jats:styled-content> occurrence.<\/jats:p>","DOI":"10.1111\/bcpt.12394","type":"journal-article","created":{"date-parts":[[2015,2,23]],"date-time":"2015-02-23T05:43:29Z","timestamp":1424670209000},"page":"213-214","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Post\u2010Injection Delirium\/Sedation Syndrome after Olanzapine Long\u2010Acting Intramuscular Injection \u2013 Who is at Risk?"],"prefix":"10.1111","volume":"117","author":[{"given":"Magdalena","family":"\u0141ukasik\u2010G\u0142\u0119bocka","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine Poznan University of Medical Sciences Poland"},{"name":"Department of Toxicology Raszeja Hospital Poznan Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karina","family":"Sommerfeld","sequence":"additional","affiliation":[{"name":"Department of Toxicology Poznan University of Medical Sciences Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Artur","family":"Te\u017cyk","sequence":"additional","affiliation":[{"name":"Department of Forensic Sciences Poznan University of Medical Sciences Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pawe\u0142","family":"Panie\u0144ski","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Poznan University of Medical Sciences Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Czes\u0142aw","family":"\u017baba","sequence":"additional","affiliation":[{"name":"Department of Forensic Sciences Poznan University of Medical Sciences Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Zieli\u0144ska\u2010Psuja","sequence":"additional","affiliation":[{"name":"Department of Toxicology Poznan University of Medical Sciences Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,3,9]]},"reference":[{"key":"e_1_2_5_2_1","volume-title":"Goodman and Gilman's Manual of Pharmacology and Therapeutics","author":"Brunton L","year":"2008"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/YIC.0000000000000040"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-244X-10-45"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-244X-10-43"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.forsciint.2013.02.010"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1517\/14656566.2012.686169"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2009.07081221"},{"key":"e_1_2_5_9_1","first-page":"60","article-title":"Olanzapine long\u2010acting post\u2010injection syndrome: a case report and brief review","volume":"41","author":"Duran\u2010Sindreu SF","year":"2013","journal-title":"Actas Esp Psiquiatr"},{"key":"e_1_2_5_10_1","first-page":"273","article-title":"Post\u2010injection delirium\/sedation syndrome following injection of olanzapine pamoate: a new syndrome in emergency psychiatry","volume":"56","author":"Buts K","year":"2014","journal-title":"Tijdschr Psychiatr"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2013.08.118"},{"key":"e_1_2_5_12_1","unstructured":"http:\/\/www.fda.gov\/safety\/medwatch\/safetyinformation\/safetyalertsforhumanmedicalproducts\/ucm357601.htm November 2014."}],"container-title":["Basic &amp; 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