{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T07:12:00Z","timestamp":1772781120589,"version":"3.50.1"},"reference-count":33,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,1,17]],"date-time":"2017-01-17T00:00:00Z","timestamp":1484611200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007397","name":"Univerzita Karlova v Praze","doi-asserted-by":"publisher","award":["P25\/1LF\/2"],"award-info":[{"award-number":["P25\/1LF\/2"]}],"id":[{"id":"10.13039\/100007397","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007397","name":"Univerzita Karlova v Praze","doi-asserted-by":"publisher","award":["P28\/1LF\/6"],"award-info":[{"award-number":["P28\/1LF\/6"]}],"id":[{"id":"10.13039\/100007397","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Basic Clin Pharma Tox"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The efficacy of treatment for intravenous elemental mercury intoxication has not been fully studied with regard to clinical outcome, and treatment recommendations vary. We treated a 41\u2010year\u2010old man with a history of drug abuse and depression who attempted suicide using 1 mL (13.53 g) metallic Hg i.v. He was admitted to the hospital 2 months later for dyspnoea and thoracic pain and was diagnosed with pneumonia. Hg deposits were seen in the lungs and extra\u2010pulmonary organs. His blood level (372 \u03bcg\/L) exceeded the population level of 5 \u03bcg\/L by more than 70 times. Dimercaptopropane sulphonate sodium (<jats:styled-content style=\"fixed-case\">DMPS<\/jats:styled-content>; 600 mg\/day orally) was administered for 14 days. One year later, the patient presented with dyspnoea on exertion, fatigue, depression and impaired sleep. His chest X\u2010ray showed multiple opacities (size up to 2.8 cm), and psychological testing revealed a selective cognitive deficit in the area of visual attentiveness, flexibility, source memory and impairment of the motor speed of the dominant upper extremity. Mercury blood level was 158 \u03bcg\/L and mercury urine output was 1380 \u03bcg\/24 hr. <jats:styled-content style=\"fixed-case\">DMPS<\/jats:styled-content> (800 mg\/day orally) was administered for 40 days; the patient eliminated up to 18 mg Hg\/day. His Hg blood level and Hg urine output belong to the highest among reported cases. In spite of the therapy, the patient's blood Hg, complaints and psychological tests showed no improvement. This case report confirms that <jats:styled-content style=\"fixed-case\">DMPS<\/jats:styled-content> does not effectively remove intravenous deposits of metallic Hg.<\/jats:p>","DOI":"10.1111\/bcpt.12725","type":"journal-article","created":{"date-parts":[[2016,12,2]],"date-time":"2016-12-02T14:04:06Z","timestamp":1480687446000},"page":"628-633","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Is Chelation Therapy Efficient for the Treatment of Intravenous Metallic Mercury Intoxication?"],"prefix":"10.1111","volume":"120","author":[{"given":"Daniela","family":"Pelclova","sequence":"first","affiliation":[{"name":"Department of Occupational Medicine Charles University First Medical Faculty and General University Hospital in Prague Prague Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stepanka","family":"Vlckova","sequence":"additional","affiliation":[{"name":"Department of Occupational Medicine Charles University First Medical Faculty and General University Hospital in Prague Prague Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ondrej","family":"Bezdicek","sequence":"additional","affiliation":[{"name":"Department of Neurology Charles University First Medical Faculty and General University Hospital in Prague Prague Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuela","family":"Vaneckova","sequence":"additional","affiliation":[{"name":"MR Unit Department of Radiodiagnostics Charles University First Medical Faculty and General University Hospital in Prague Prague Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pavel","family":"Urban","sequence":"additional","affiliation":[{"name":"Department of Occupational Medicine Charles University First Medical Faculty and General University Hospital in Prague Prague Czech Republic"},{"name":"National Institute of Public Health Centre for Industrial Hygiene and Occupational Medicine Prague Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petr","family":"Ridzon","sequence":"additional","affiliation":[{"name":"Department of Occupational Medicine Charles University First Medical Faculty and General University Hospital in Prague Prague Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pavel","family":"Diblik","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Charles University First Medical Faculty and General University Hospital in Prague Prague Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomas","family":"Navratil","sequence":"additional","affiliation":[{"name":"J. 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