{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T22:21:12Z","timestamp":1759530072647},"reference-count":9,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,3,7]],"date-time":"2017-03-07T00:00:00Z","timestamp":1488844800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Basic Clin Pharma Tox"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Lithium is recommended in bipolar disorder and can be accompanied by significant toxicity in pregnant women. A 25\u2010year\u2010old single\u2010gestation pregnant woman (28 weeks) was referred with suspicion of lithium toxicity. Serum lithium was 2.1 meq\/L. Despite conservative therapy with intravenous fluids, lithium concentration increased to 5.0 meq\/L 6 hr after admission mandating an emergent haemodialysis during which foetal heart rate decreased to 90 bpm. The gynaecologist ordered termination of pregnancy while the mother was still on haemodialysis. Caesarean section was carried out, but the born baby had an apgar of 2 and died. Autopsy findings of the foetus revealed a cord blood lithium concentration of 4.8 mEq\/L with no physical abnormalities. Although the foetus had the signs\/symptoms of distress, continuation of haemodialysis could probably have saved it as it saved its mother's life. In lithium toxicity in a pregnant woman, it is reasonable to continue haemodialysis even with the signs and symptoms of foetal distress. In similar situations, emergency haemodialysis instead of immediate caesarean section should be considered.<\/jats:p>","DOI":"10.1111\/bcpt.12747","type":"journal-article","created":{"date-parts":[[2016,12,19]],"date-time":"2016-12-19T21:52:44Z","timestamp":1482184364000},"page":"509-511","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Lithium Toxicity in a Pregnant Woman"],"prefix":"10.1111","volume":"120","author":[{"given":"Nasim","family":"Zamani","sequence":"first","affiliation":[{"name":"Toxicological Research Center Department of Clinical Toxicology Loghman Hakim Hospital School of Medicine Shahid Beheshti University of Medical Sciences Tehran Iran"},{"name":"Excellence Center of Clinical Toxicology Iranian Ministry of Health Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryam","family":"Paeezi","sequence":"additional","affiliation":[{"name":"Toxicological Research Center Department of Clinical Toxicology Loghman Hakim Hospital School of Medicine Shahid Beheshti University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hossein","family":"Hassanian\u2010Moghaddam","sequence":"additional","affiliation":[{"name":"Toxicological Research Center Department of Clinical Toxicology Loghman Hakim Hospital School of Medicine Shahid Beheshti University of Medical Sciences Tehran Iran"},{"name":"Excellence Center of Clinical Toxicology Iranian Ministry of Health Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,3,7]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.10021014"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2014.14030409"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.161.4.608"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000286343"},{"key":"e_1_2_5_6_1","first-page":"983","volume-title":"Goldfrank's Toxicologic Emergencies","author":"Greller HA","year":"2015"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8627(03)00042-7"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.58.10.840-a"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijoa.2007.09.014"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1993.tb15221.x"}],"container-title":["Basic &amp; Clinical Pharmacology &amp; Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fbcpt.12747","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bcpt.12747","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T11:21:44Z","timestamp":1695554504000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/bcpt.12747"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,7]]},"references-count":9,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["10.1111\/bcpt.12747"],"URL":"https:\/\/doi.org\/10.1111\/bcpt.12747","archive":["Portico"],"relation":{},"ISSN":["1742-7835","1742-7843"],"issn-type":[{"value":"1742-7835","type":"print"},{"value":"1742-7843","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,7]]},"assertion":[{"value":"2016-10-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-12-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-03-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}