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We aimed to analyse gait and balance impairment in a group of Czech methanol poisoning survivors. We examined 43 patients (age 46 \u00b1 13 years) 2\u20138 months after methanol poisoning and 43 healthy controls. Investigations contained a shortened version of Falls Efficacy Scale (<jats:styled-content style=\"fixed-case\">FES<\/jats:styled-content>), clinical tests of gait and balance including Timed Up and Go test (<jats:styled-content style=\"fixed-case\">TUG<\/jats:styled-content>) and gait analysis using GaitRite<jats:sup>\u00ae<\/jats:sup> system, neurological and neuropsychological examination, brain imaging, <jats:styled-content style=\"fixed-case\">EMG<\/jats:styled-content> and tests of alcohol consumption. Nineteen patients admitted balance and gait impairment according to <jats:styled-content style=\"fixed-case\">FES<\/jats:styled-content>. Mild to moderate parkinsonian signs showed seven patients. Patients were slower (8.8 <jats:italic>versus<\/jats:italic> 5.7 s, <jats:italic>p<\/jats:italic> &lt; 0.001) and performed more steps (11.1 <jats:italic>versus<\/jats:italic> 7.9, <jats:italic>p<\/jats:italic> &lt; 0.001) in <jats:styled-content style=\"fixed-case\">TUG<\/jats:styled-content> compared with the controls. Gait analysis revealed shorter step length (76.5 <jats:italic>versus<\/jats:italic> 88.7 cm, <jats:italic>p<\/jats:italic> &lt; 0.001), increased double support phase (18.8 <jats:italic>versus<\/jats:italic> 15.5%, <jats:italic>p<\/jats:italic> &lt; 0.001) and wider base of support (11.3 <jats:italic>versus<\/jats:italic> 9.6 cm, <jats:italic>p<\/jats:italic> = 0.006) in patients. Eleven patients had deficit of executive function and performed higher cadence compared to the patients with normal execution (122.7 <jats:italic>versus<\/jats:italic> 115.0 step\/min., <jats:italic>p<\/jats:italic> = 0.025). Lower limb polyneuropathy was verified in nine patients, without relation with gait or balance parameters. Neuroimaging revealed lesions mainly in the basal ganglia. Methanol poisoning survivors presented slower wide\u2010based gait with shortened steps corresponding with frontal gait disorder. Higher stepping cadence associated with executive deficit supported the evidence of frontal lobe dysfunction related to impairment of basal ganglia and connections in frontal cortico\u2010basal ganglia loops.<\/jats:p>","DOI":"10.1111\/bcpt.12853","type":"journal-article","created":{"date-parts":[[2017,7,19]],"date-time":"2017-07-19T16:06:40Z","timestamp":1500480400000},"page":"176-182","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Gait and Balance Impairment after Acute Methanol Poisoning"],"prefix":"10.1111","volume":"122","author":[{"given":"Kamila","family":"Peterov\u00e1","sequence":"first","affiliation":[{"name":"Department of Neurology Charles University First Faculty of Medicine and General University Hospital Prague Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hana","family":"Bro\u017eov\u00e1","sequence":"additional","affiliation":[{"name":"Department of Neurology 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