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However, the pandemic may have negatively impacted health care services for chronic diseases. The aim of this study was to assess initiations of antihypertensive medicines in patients infected by COVID\u201019.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cohort study including all Swedish residents 20\u201380\u2009years old with a COVID\u201019 positive test compared with an unexposed group without COVID\u201019 matched for age, sex, and index date (date of confirmed COVID\u201019). Data were collected within SCIFI\u2010PEARL, a study including linked data on COVID tests, hospital diagnoses, dispensed prescriptions, and socioeconomic data from Swedish national registers. Initiations of different antihypertensive drugs were studied from March 2020 until October 2020. Associations between COVID\u201019 and initiation of antihypertensives were assessed by a multivariable Cox proportional hazards model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 224\u2009582 patients (exposed and unexposed) were included. After adjusting for cardiovascular comorbidities and education level, ACEi was the most commonly initiated antihypertensive agent to patients with COVID\u201019. Hazard ratio and 95% confidence interval for initiation of drug therapy was 1.83 [1.53\u20132.19] for ACEi, followed by beta\u2010blockers 1.74 [1.55\u20131.95], calcium channel blockers 1.61 [1.41\u20131.83], angiotensin receptor blockers 1.61 [1.40\u20131.86], and diuretics 1.53 [1.32\u20131.77].<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>All antihypertensive medicines were initiated more frequently in COVID\u201019 patients. This can either be associated with hypertension caused by the COVID\u201019 infection, more frequent diagnosis of hypertension among people with COVID\u201019 since they consult health care, or residual confounding factors not adjusted for in the study.<\/jats:p><\/jats:sec>","DOI":"10.1111\/bcpt.13766","type":"journal-article","created":{"date-parts":[[2022,6,21]],"date-time":"2022-06-21T01:28:58Z","timestamp":1655774938000},"page":"196-204","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Initiation of antihypertensive drugs to patients with confirmed COVID\u201019\u2014A population\u2010based cohort study in Sweden"],"prefix":"10.1111","volume":"131","author":[{"given":"Salar Issa","family":"Mousa","sequence":"first","affiliation":[{"name":"Pharmacoepidemiology &amp; Social Pharmacy, Department of Pharmacy Uppsala University  Uppsala Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0892-5668","authenticated-orcid":false,"given":"Fredrik","family":"Nyberg","sequence":"additional","affiliation":[{"name":"School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy University of Gothenburg  Gothenburg Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8118-4988","authenticated-orcid":false,"given":"Mohammadhossein","family":"Hajiebrahimi","sequence":"additional","affiliation":[{"name":"Pharmacoepidemiology &amp; Social Pharmacy, Department of Pharmacy Uppsala University  Uppsala Sweden"},{"name":"Department of Statistics and Epidemiology Public Health Faculty, Golestan University of Medical Sciences  Gorgan Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecka","family":"Bertilsson","sequence":"additional","affiliation":[{"name":"National Diabetes Register Centre of Registers V\u00e4stra G\u00f6taland  Gothenburg Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonatan","family":"N\u00e5tman","sequence":"additional","affiliation":[{"name":"National Diabetes Register Centre of Registers V\u00e4stra G\u00f6taland  Gothenburg Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ailiana","family":"Santosa","sequence":"additional","affiliation":[{"name":"School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy University of Gothenburg  Gothenburg Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0531-2516","authenticated-orcid":false,"given":"Bj\u00f6rn","family":"Wettermark","sequence":"additional","affiliation":[{"name":"Pharmacoepidemiology &amp; Social Pharmacy, Department of Pharmacy Uppsala University  Uppsala Sweden"},{"name":"Pharmacy Centre, Faculty of Medicine Vilnius University  Vilnius Lithuania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,7,6]]},"reference":[{"volume-title":"Coronavirus Disease 2019 (COVID\u201019)","year":"2020","author":"CDC","key":"e_1_2_7_2_1"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/joim.13184"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.31083\/j.rcm2301028"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(20)31067\u20109"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dsx.2020.06.050"},{"key":"e_1_2_7_7_1","unstructured":"WHO NCD Department.Rapid assessment of service delivery for NCDs during the COVID\u201019 pandemic. 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