{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T00:58:33Z","timestamp":1778720313703,"version":"3.51.4"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T00:00:00Z","timestamp":1749513600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Basic Clin Pharma Tox"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Pharmacist\u2010led deprescribing is an approach of addressing polypharmacy in the long\u2010term care (LTC) setting. However, the sustainability of this practice has not been widely studied. This study describes facilitators and barriers to pharmacist\u2010led deprescribing from pre\u2010 and post\u2010surveys completed as part of a randomized controlled antihypertensive deprescribing trial in Alberta, Canada. The surveys, targeting facilitators and barriers to deprescribing, were developed based on current evidence and designed through an iterative process with pharmacist input and consist of open\u2010 and closed\u2010ended questions. Nine pharmacists completed both surveys (seven female; five have been a pharmacist \u226510\u2009years; and eight had their Additional Prescribing Authority [authority to prescribe to full scope of practice]). The key facilitators were (1) pharmacist confidence and attitude toward deprescribing, (2) sufficient patient data, and (3) minimal tools and education required. The key barriers included (1) pharmacist perception of not being the primary decision maker on prescribing decisions, (2) insufficient support from residents' families and physicians, and (3) additional time required. These facilitators and barriers were all identified pre\u2010deprescribing, and confirmed, and more evident post\u2010deprescribing. These barriers will make it challenging for pharmacists to incorporate deprescribing antihypertensives into routine care.<\/jats:p>","DOI":"10.1111\/bcpt.70060","type":"journal-article","created":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T03:09:07Z","timestamp":1749611347000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Barriers and Facilitators to Pharmacist\u2010Led Deprescribing of Antihypertensives in Long\u2010Term Care: A Survey\u2010Based Study"],"prefix":"10.1111","volume":"137","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8762-9383","authenticated-orcid":false,"given":"Ana","family":"Vucenovic","sequence":"first","affiliation":[{"name":"Department of Family Medicine University of Alberta  Edmonton Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roni\u00a0Y.","family":"Kraut","sequence":"additional","affiliation":[{"name":"Department of Family Medicine University of Alberta  Edmonton Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donna\u00a0P.","family":"Manca","sequence":"additional","affiliation":[{"name":"Department of Family Medicine University of Alberta  Edmonton Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheryl\u00a0A.","family":"Sadowski","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy and Pharmaceutical Sciences University of Alberta  Edmonton Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,6,10]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40266\u2010018\u20100537\u20103"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2019.10.022"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2024.105305"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahjo.2022.100166"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.12732"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.4140\/TCP.n.2023.506"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.14101"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/hsc.14099"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sapharm.2023.01.013"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102024\u2010084619"},{"key":"e_1_2_10_12_1","unstructured":"RE\u2010Aim accessed November 8 2024 Available:https:\/\/re\u2010aim.org\/."},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afab250"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcpt.13944"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sapharm.2024.04.014"},{"key":"e_1_2_10_16_1","unstructured":"Canadian Pharmacists Association Scope of Practice accessed November 8 2024 https:\/\/www.pharmacists.ca\/advocacy\/scope\u2010of\u2010practice\/."},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-64477-2_73"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sapharm.2024.12.008"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sapharm.2009.11.008"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1080\/13561820.2019.1609432"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/07334648211069553"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11606\u2010021\u201006965\u20105"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj\u20102023\u2010074892"}],"container-title":["Basic &amp; Clinical Pharmacology &amp; Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bcpt.70060","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T06:53:13Z","timestamp":1750920793000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/bcpt.70060"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,10]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1111\/bcpt.70060"],"URL":"https:\/\/doi.org\/10.1111\/bcpt.70060","archive":["Portico"],"relation":{},"ISSN":["1742-7835","1742-7843"],"issn-type":[{"value":"1742-7835","type":"print"},{"value":"1742-7843","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,10]]},"assertion":[{"value":"2025-01-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70060"}}