{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T01:43:50Z","timestamp":1780451030095,"version":"3.54.1"},"reference-count":36,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T00:00:00Z","timestamp":1757462400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T00:00:00Z","timestamp":1757462400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Basic Clin Pharma Tox"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>While deprescribing benzodiazepines and related drugs (BZRDs) is crucial for preventing prolonged use and their associated adverse effects, it presents challenges from a healthcare perspective, because of limited resources and time. Recently, a pharmacist\u2010led deprescribing of BZRDs in the treatment of insomnia was introduced in Helsinki's primary care health centres. To explore pharmacists' and physicians' insights, qualitative semi\u2010structured interviews were conducted via Microsoft Teams with physicians and pharmacists involved in a pharmacist\u2010led deprescribing. The interviews were recorded, transcribed verbatim and analysed abductively. A total of four pharmacists and four physicians from four health centres participated in this study. Pharmacist\u2010led deprescribing was perceived as having positive outcomes and as being efficient, particularly in saving physicians' time and resources. Various patient\u2010related facilitators and barriers were identified, with patient motivation and willingness being the most cited. Suggestions for improvement included establishing clear criteria for deprescribing, clarifying the roles in the process flow, providing enhanced deprescribing guidance and educational materials and enhancing the patient\u2010centred approach by actively involving patients in the decision\u2010making process and considering the patient's overall situation. Overall, the pharmacist\u2010led model was seen as a promising and resource\u2010efficient approach to deprescribing BZRDs in primary care health centres.<\/jats:p>","DOI":"10.1111\/bcpt.70106","type":"journal-article","created":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T09:54:36Z","timestamp":1757498076000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Insights Into Pharmacist\u2010Led Deprescribing of Benzodiazepines and Related Drugs: A Qualitative Study With Physicians and Pharmacists"],"prefix":"10.1111","volume":"137","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-4184-1620","authenticated-orcid":false,"given":"Miro","family":"Korppas","sequence":"first","affiliation":[{"name":"School of Pharmacy University of Eastern Finland  Kuopio Finland"},{"name":"HUS Pharmacy, Helsinki University Hospital and University of Helsinki  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5069-5045","authenticated-orcid":false,"given":"Miia","family":"Tiihonen","sequence":"additional","affiliation":[{"name":"School of Pharmacy University of Eastern Finland  Kuopio Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marika","family":"Buch\u00a0Lund","sequence":"additional","affiliation":[{"name":"Health and Social Services  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3136-5972","authenticated-orcid":false,"given":"Kirsi","family":"Kvarnstr\u00f6m","sequence":"additional","affiliation":[{"name":"HUS Pharmacy, Helsinki University Hospital and University of Helsinki  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,10]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.3109\/13651500903447810"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2014.1763"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40266\u2010018\u20100544\u20104"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s41999\u2010022\u201000731\u20104"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/416864"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11606\u2010019\u201005098\u20100"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/add.14981"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.18372"},{"issue":"5","key":"e_1_2_12_10_1","first-page":"339","article-title":"Deprescribing Benzodiazepine Receptor Agonists","volume":"64","author":"Pottie K.","year":"2018","journal-title":"Canadian Family Physician"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/metabo11040254"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13012\u2010022\u201001206\u20107"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.7812\/TPP\/17\u2010157"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00228\u2010017\u20102257\u20108"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.2147\/PPA.S323846"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rcsop.2023.100328"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/17151635211014918"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.japh.2022.09.025"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11096\u2010023\u201001637\u20102"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sapharm.2019.02.004"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/hex.13392"},{"key":"e_1_2_12_22_1","unstructured":"Finnish National Board on Research Integrity (TENK).The Finnish Code of Conduct for Research Integrity and Procedures for Handling Alleged Violations of Research Integrity in Finland.2023. Accessed May 3 2024 https:\/\/tenk.fi\/sites\/default\/files\/2023\u201005\/RI_Guidelines_2023.pdf."},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/ACM.0000000000000388"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/intqhc\/mzm042"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcpt.13944"},{"key":"e_1_2_12_26_1","unstructured":"Medical Research Act 488\/1999. Accessed May 3 2024 https:\/\/www.finlex.fi\/fi\/laki\/kaannokset\/1999\/en19990488.pdf."},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11096\u2010022\u201001449\u2010w"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcpt.13878"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.japh.2022.05.019"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.12386"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102017\u2010015959"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.5535"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.3399\/bjgp19X701753"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ps.201200089"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.2165\/00002512\u2010200320110\u201000004"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913\u2010015\u20100726\u20102"},{"key":"e_1_2_12_37_1","first-page":"27","volume-title":"Theory at a Glance: A Guide for Health Promotion Practice","author":"Rimer B. K.","year":"2005"}],"container-title":["Basic &amp; Clinical Pharmacology &amp; Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bcpt.70106","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/bcpt.70106","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bcpt.70106","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T11:59:54Z","timestamp":1772971194000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/bcpt.70106"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,10]]},"references-count":36,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1111\/bcpt.70106"],"URL":"https:\/\/doi.org\/10.1111\/bcpt.70106","archive":["Portico"],"relation":{},"ISSN":["1742-7835","1742-7843"],"issn-type":[{"value":"1742-7835","type":"print"},{"value":"1742-7843","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,10]]},"assertion":[{"value":"2025-02-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70106"}}