{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T06:22:06Z","timestamp":1787552526136,"version":"build-2736575974"},"reference-count":19,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T00:00:00Z","timestamp":1787356800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T00:00:00Z","timestamp":1787356800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Basic Clin Pharma Tox"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Poisoning with ethylene glycol and methanol remains a recurrent problem in Scandinavia. This study aimed to describe the epidemiology, exposure circumstances, clinical characteristics and management of toxic alcohol poisonings reported to the Danish Poison Information Centre to support preventive initiatives and improve toxicological counselling.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>All calls concerning confirmed or suspected ingestion of ethylene glycol or methanol registered by the Danish Poison Information Centre between 2006 and 2022 were reviewed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 592 exposures involving ethylene glycol (85%) or methanol were identified. Children accounted for 25% of exposures and adults for 61%, with a predominance of males (73%). Accidental ingestion accounted for 71% of exposures. In more than 60% of cases, the Danish Poison Information Centre assessed a risk of moderate to potentially fatal poisoning. Hospitalization was recommended in approximately 70% of cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Ethylene glycol poisoning was more common than methanol poisoning and was primarily associated with accidental ingestion of engine coolant products following inappropriate storage or handling. Many patients were referred for hospital evaluation because risk assessment relied mainly on circumstantial information suggesting potential severe poisoning.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Toxic alcohol poisoning in Denmark is primarily caused by accidental ethylene glycol ingestion. Rapid blood analysis of toxic alcohols may reduce delayed treatment and unnecessary hospitalization.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bcpt.70291","type":"journal-article","created":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T07:35:22Z","timestamp":1787384122000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Poisoning With Toxic Alcohols in Denmark"],"prefix":"10.1111","volume":"139","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-6920-7018","authenticated-orcid":false,"given":"Thomas","family":"Jacobsen","sequence":"first","affiliation":[{"name":"Department of Occupational and Environmental Medicine University Hospital Copenhagen, Bispebjerg and Frederiksberg Hospital  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja Julie","family":"Huusom","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Medicine University Hospital Copenhagen, Bispebjerg and Frederiksberg Hospital  Copenhagen Denmark"},{"name":"Department of Clinical Pharmacology University Hospital Copenhagen, Bispebjerg  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9974-2738","authenticated-orcid":false,"given":"Tonny Studsgaard","family":"Petersen","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology University Hospital Copenhagen, Bispebjerg  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stinna","family":"Skaaby","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Medicine University Hospital Copenhagen, Bispebjerg and Frederiksberg Hospital  Copenhagen Denmark"},{"name":"University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula Edeusa Cristina","family":"Hammer","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Medicine University Hospital Copenhagen, Bispebjerg and Frederiksberg Hospital  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,22]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"1","article-title":"F\u00f6renklad analys av etylenglykol kan ge snabbare diagnos vid f\u00f6rgiftningsfall","volume":"117","author":"Helander A.","year":"2020","journal-title":"L\u00e4kartidningen"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.legalmed.2023.102279"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/10826081003682859"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/03000605221081427"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1615295"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.2005.01521.x"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2010.12.005"},{"issue":"19","key":"e_1_2_10_9_1","first-page":"2065","article-title":"Sv\u00e6r metabolisk acidose efter ethylenglykolforgiftning","volume":"167","author":"Ulstrup A.","year":"2005","journal-title":"Ugeskrift for Laeger"},{"issue":"34","key":"e_1_2_10_10_1","first-page":"2907","article-title":"\u00c6tylenglykolforgiftning","volume":"166","author":"B\u00f8mler B.","year":"2004","journal-title":"Ugeskrift for Laeger"},{"issue":"15","key":"e_1_2_10_11_1","first-page":"2250","article-title":"Tr\u00e6spritforgiftning hos alkoholmisbrugere","volume":"156","author":"Kristensen I. B.","year":"1994","journal-title":"Ugeskrift for Laeger"},{"issue":"22","key":"e_1_2_10_12_1","first-page":"1866","article-title":"Ekstrem acidose hos bevidstl\u00f8s patient \u2013 formodet forgiftning med k\u00f8lerv\u00e6ske","volume":"171","author":"Lundgaard P.","year":"2009","journal-title":"Ugeskrift for Laeger"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.forsciint.2004.11.012"},{"key":"e_1_2_10_14_1","first-page":"1","article-title":"BCPT 2026 Policy for Experimental and Clinical Studies","volume":"137","author":"Tveden\u2010Nyborg P.","year":"2026","journal-title":"Basic & Clinical Pharmacology & Toxicology"},{"issue":"3","key":"e_1_2_10_15_1","first-page":"329","article-title":"Risk of Fatal Alcohol Poisoning by Marital and Occupational Status","volume":"20","author":"Poikolainen K.","year":"1985","journal-title":"Alcohol and Alcoholism"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1080\/15563650.2019.1636992"},{"key":"e_1_2_10_17_1","article-title":"B\u00e4ttre tillg\u00e5ng till provsvar f\u00f6r toxiska alkoholer kan r\u00e4dda liv","volume":"119","author":"Helander A.","year":"2022","journal-title":"L\u00e4kartidningen"},{"key":"e_1_2_10_18_1","first-page":"699","article-title":"Methanol Poisoning. Emergency Measures, Diagnostic and Therapeutic Problems During the Kristiansand Outbreak in 1979","volume":"101","author":"Sejersted O. M.","year":"1981","journal-title":"Tidsskrift for den Norske L\u00e6geforening"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.3109\/15563659209017942"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/jat\/bkv044"}],"container-title":["Basic &amp; Clinical Pharmacology &amp; Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bcpt.70291","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/bcpt.70291","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bcpt.70291","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T06:09:00Z","timestamp":1787551740000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/bcpt.70291"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,22]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1111\/bcpt.70291"],"URL":"https:\/\/doi.org\/10.1111\/bcpt.70291","archive":["Portico"],"relation":{},"ISSN":["1742-7835","1742-7843"],"issn-type":[{"value":"1742-7835","type":"print"},{"value":"1742-7843","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,22]]},"assertion":[{"value":"2026-05-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70291"}}