{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T13:27:15Z","timestamp":1777901235978,"version":"3.51.4"},"reference-count":30,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2012,9,21]],"date-time":"2012-09-21T00:00:00Z","timestamp":1348185600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bipolar Disorders"],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:p>Finseth PI, Morken G, Andreassen OA, Malt UF, Vaaler AE. Risk factors related to lifetime suicide attempts in acutely admitted bipolar disorder inpatients. \u2028Bipolar Disord 2012: 14: 727\u2013734. \u00a9 2012 The Authors. \u2028Journal compilation \u00a9 2012 John Wiley &amp; Sons A\/S.<\/jats:p><jats:p><jats:bold>Objective:\u2002<\/jats:bold> The main aim of this study was to assess possible clinical characteristics of acutely admitted bipolar I disorder (BD\u2010I) and bipolar II disorder (BD\u2010II) inpatients at high risk of suicide by comparing patients who had made one or several serious suicide attempts with patients who had not.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> A total of 206 consecutive patients (mean age 42\u2003\u00b1\u200315\u2003years; 54.9% women) with DSM\u2013IV diagnosed BD\u2010I (n\u2003=\u2003140) and BD\u2010II (n\u2003=\u200366) acutely admitted to a single psychiatric hospital department from November 2002 through June 2009 were included. Using a detailed retrospective questionnaire, patients with a history of a serious suicide attempt were compared to those with no history of a suicide attempt.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Ninety\u2010three patients (45.1%) had a history of one or more serious suicide attempts. These constituted 60 (42.9%) of the BD\u2010I patients and 33 (50%) of the BD\u2010II patients (no significant difference). Lifetime suicide attempt was associated with a higher number of hospitalizations due to depression (p\u2003&lt;\u20030.0001), antidepressant (AD)\u2010induced hypomania\/mania (p\u2003=\u20030.033), AD\u2010 and\/or alcohol\u2010induced affective episodes (p\u2003=\u20030.009), alcohol and\/or substance use (p\u2003=\u20030.002), and a family history of alcohol abuse and\/or affective disorder (p\u2003=\u20030.01). Suicide attempt was negatively associated with a higher Positive and Negative Syndrome Scale for Schizophrenia (PANSS) Positive Subscale score (p\u2003=\u20030.022) and more hospitalizations due to mania (p\u2003=\u20030.006).<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> The lifetime suicide attempt rate in BD inpatients is high. Risk factors of suicide attempts were: (i) a predominant depressive course of illness, (ii) comorbid alcohol and substance use disorders, and (iii) a history of AD\u2010 and\/or alcohol\u2010induced affective episodes. Risk\u2010reducing factors were a preponderant manic or psychotic course of the illness. These risk factors may be signs of a clinical subgroup at risk of suicidal behaviour, and seem to be important for suicide risk assessment in acutely admitted BD patients.<\/jats:p>","DOI":"10.1111\/bdi.12004","type":"journal-article","created":{"date-parts":[[2012,9,21]],"date-time":"2012-09-21T12:31:07Z","timestamp":1348230667000},"page":"727-734","source":"Crossref","is-referenced-by-count":42,"title":["Risk factors related to lifetime suicide attempts in acutely admitted bipolar disorder inpatients"],"prefix":"10.1111","volume":"14","author":[{"given":"Per I","family":"Finseth","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gunnar","family":"Morken","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ole A","family":"Andreassen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrik 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