{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T21:50:39Z","timestamp":1783029039194,"version":"3.54.6"},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,1,10]],"date-time":"2013-01-10T00:00:00Z","timestamp":1357776000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bipolar Disorders"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:p>Morriss R, Yang M, Chopra A, Bentall R, Paykel E, Scott J. Differential effects of depression and mania symptoms on social adjustment: prospective study in bipolar disorder. \u2028Bipolar Disord 2013: 15: 80\u201391. \u00a9 2013 John Wiley &amp; Sons A\/S. Published by Blackwell Publishing Ltd.<\/jats:p><jats:p><jats:bold>Objectives:\u2002<\/jats:bold> Previous studies of social adjustment in bipolar disorder have been cross\u2010sectional and small in sample size, have examined a limited number of roles, or were not controlled for baseline mood and other clinical, social, or treatment confounders. We aimed to prospectively explore the strength and stability of correlations between depression and mania\u2010type symptoms and impairment in a broad range of social adjustment roles and domains.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> Multilevel modeling analysis of correlation coefficients between depression and mania\u2010type symptoms with roles and domains of the modified social adjustment scale (overall, work, social\/leisure, extended family, marital, parental social adjustment roles, performance, interpersonal behavior, friction, dependency, overactivity domains) was used. Interview assessments were made at eight\u2010week intervals beginning at eight weeks and continuing through 72\u2003weeks after baseline in 253 patients in a multicenter randomized controlled trial.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> After controlling for baseline mood episodes, and other clinical, social, and treatment variables, depression symptoms showed strong and stable correlations over time with performance, overall social adjustment, and the work role; and a moderate but stable relationship with interpersonal behavior. The relationships of depression symptoms with the other roles were weak, non\u2010significant, or not stable. For mania\u2010type symptoms, only the correlation with interpersonal friction was moderately strong and reasonably stable over time. Mood episodes, substance use disorder, and borderline\/antisocial personality disorder increased role impairment, while employment and marriage mildly decreased it.<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> Depression and mania\u2010type symptoms have specific effects on social adjustment in bipolar I disorder. Depression symptoms are correlated strongly with performance and moderately with interpersonal behavior, while mania\u2010type symptoms are correlated moderately with interpersonal friction.<\/jats:p>","DOI":"10.1111\/bdi.12036","type":"journal-article","created":{"date-parts":[[2013,1,10]],"date-time":"2013-01-10T11:15:59Z","timestamp":1357816559000},"page":"80-91","source":"Crossref","is-referenced-by-count":15,"title":["Differential effects of depression and mania symptoms on social adjustment: prospective study in bipolar disorder"],"prefix":"10.1111","volume":"15","author":[{"given":"Richard","family":"Morriss","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arun","family":"Chopra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Bentall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugene","family":"Paykel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Scott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,1,10]]},"reference":[{"key":"e_1_2_9_2_2","volume-title":"The Depressed Woman. 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