{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T14:27:21Z","timestamp":1791210441658,"version":"4.1.0"},"reference-count":41,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,5,7]],"date-time":"2013-05-07T00:00:00Z","timestamp":1367884800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bipolar Disorders"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Women who experience postpartum psychosis (<jats:styled-content style=\"fixed-case\">PP<\/jats:styled-content>) seek guidance on further pregnancies and risk of illness; however, empirical data are limited. This study describes reproductive and mental health outcomes in women diagnosed with<jats:styled-content style=\"fixed-case\">PP<\/jats:styled-content>and examines clinical risk factors as predictors of further illness.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective cohort design was used; 116 women who experienced episodes of mania or depression with psychotic features within six weeks of childbirth were recruited. All subjects underwent clinical diagnostic interviews and medical case notes were reviewed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Only 33% of women had an antecedent history, of which 34% had bipolar disorder and 55% unipolar depression. Only 58% of those with<jats:styled-content style=\"fixed-case\">PP<\/jats:styled-content>in their first pregnancy had a subsequent pregnancy, and 18% of marriages ended following the<jats:styled-content style=\"fixed-case\">PP<\/jats:styled-content>episode. Clinical presentation at the time of initial episode did not influence the timing of the onset of symptoms, treatment, or recovery. Although 86% of patients received treatment within 30\u00a0days of onset, 26% of women reported ongoing symptoms at a year after delivery. The recurrence rate of<jats:styled-content style=\"fixed-case\">PP<\/jats:styled-content>was 54.4%; a longer duration of the index episode (p\u00a0&lt;\u00a00.05) and longer latency between the index<jats:styled-content style=\"fixed-case\">PP<\/jats:styled-content>and next pregnancy predicted a subsequent<jats:styled-content style=\"fixed-case\">PP<\/jats:styled-content>. The rate of subsequent non\u2010puerperal episodes was 69%, and all these episodes were bipolar.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Postpartum psychosis is difficult to predict in women with no antecedent history and is associated with a high rate of subsequent puerperal and non\u2010puerperal illness. Risk of further illness needs to be conveyed in order to allow fully informed decisions to be made regarding future pregnancies.<\/jats:p><\/jats:sec>","DOI":"10.1111\/bdi.12071","type":"journal-article","created":{"date-parts":[[2013,5,7]],"date-time":"2013-05-07T12:11:18Z","timestamp":1367928678000},"page":"394-404","source":"Crossref","is-referenced-by-count":91,"title":["Reproductive outcomes and risk of subsequent illness in women diagnosed with postpartum psychosis"],"prefix":"10.1111","volume":"15","author":[{"given":"Emma Robertson","family":"Blackmore","sequence":"first","affiliation":[{"name":"Departments of Psychiatry and Biostatistics and Computational Biology University of Rochester Medical Center Rochester NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David R","family":"Rubinow","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of North Carolina Chapel Hill NC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas G","family":"O'Connor","sequence":"additional","affiliation":[{"name":"Departments of Psychiatry and Biostatistics and Computational Biology University of Rochester Medical Center Rochester NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Liu","sequence":"additional","affiliation":[{"name":"Departments of Psychiatry and Biostatistics and Computational Biology University of Rochester Medical Center Rochester NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wan","family":"Tang","sequence":"additional","affiliation":[{"name":"Departments of Psychiatry and Biostatistics and Computational Biology University of Rochester Medical Center Rochester NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nick","family":"Craddock","sequence":"additional","affiliation":[{"name":"Department of Psychological Medicine Cardiff University Cardiff UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Jones","sequence":"additional","affiliation":[{"name":"Department of Psychological Medicine Cardiff University Cardiff UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,5,7]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.296.21.2582"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.172.6.521"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.186.6.453"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2008.08121899"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)69789-4"},{"key":"e_1_2_7_7_1","unstructured":"CEMACH.The Confidential Enquiry into Maternal and Child Health 2007. 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