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However, frequencies and risk factors of SI<\/jats:styled-content>\/SA<\/jats:styled-content> and targeted intervention trials for SI<\/jats:styled-content>\/SA<\/jats:styled-content> in PBD<\/jats:styled-content> have not been reviewed systematically.<\/jats:p><\/jats:sec>Methods<\/jats:title>We conducted a systematic PubMed review, searching for articles reporting on prevalences\/incidences, correlates and intervention studies targeting SI<\/jats:styled-content>\/SA<\/jats:styled-content> in PBD<\/jats:styled-content>. Weighted means were calculated, followed by an exploratory meta\u2010regression of SI<\/jats:styled-content> and SA<\/jats:styled-content> correlates.<\/jats:p><\/jats:sec>Results<\/jats:title>Fourteen studies (n\u00a0=\u00a01595), in which 52.1% of patients were male and the mean age was 14.4\u00a0years, reported data on SI<\/jats:styled-content>\/SA<\/jats:styled-content> prevalence (N\u00a0=\u00a013, n\u00a0=\u00a01508) and\/or correlates (N\u00a0=\u00a010, n\u00a0=\u00a01348) in PBD<\/jats:styled-content>. Weighted mean prevalences were: past SI<\/jats:styled-content> = 57.4%, past SA<\/jats:styled-content> = 21.3%, current SI<\/jats:styled-content> = 50.4%, and current SA<\/jats:styled-content> = 25.5%; incidences (mean 42\u00a0months of follow\u2010up) were: SI<\/jats:styled-content> = 14.6% and SA<\/jats:styled-content> = 14.7%. Regarding significant correlates, SI<\/jats:styled-content> (N\u00a0=\u00a03) was associated with a higher percentage of C<\/jats:styled-content>aucasian race, narrow (as opposed to broad) PBD<\/jats:styled-content> phenotype, younger age, and higher quality of life than SA<\/jats:styled-content><\/jats:italic>. Significant correlates of SA<\/jats:styled-content> (N\u00a0=\u00a010) included female sex, older age, earlier illness onset, more severe\/episodic PBD<\/jats:styled-content>, mixed episodes, comorbid disorders, past self\u2010injurious behavior\/SI<\/jats:styled-content>\/SA<\/jats:styled-content>, physical\/sexual abuse, parental depression, family history of suicidality, and poor family functioning. Race, socioeconomic status, living situation, and life events were not clearly associated with SA<\/jats:styled-content>. In a meta\u2010regression analysis, bipolar I disorder and comorbid attention\u2010deficit hyperactivity disorder were significantly associated with SA<\/jats:styled-content>. Only one open label study targeting the reduction of SI<\/jats:styled-content>\/SA<\/jats:styled-content> in PBD<\/jats:styled-content> was identified.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>SI<\/jats:styled-content> and SA<\/jats:styled-content> are very common but under\u2010investigated in PBD<\/jats:styled-content>. Exploration of predictors and protective factors is imperative for the establishment of effective preventive and intervention strategies, which are urgently needed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/bdi.12094","type":"journal-article","created":{"date-parts":[[2013,7,5]],"date-time":"2013-07-05T12:03:31Z","timestamp":1373025811000},"page":"507-523","source":"Crossref","is-referenced-by-count":146,"title":["Suicidal ideation and suicide attempts in children and adolescents with bipolar disorder: a systematic review of prevalence and incidence rates, correlates, and targeted interventions"],"prefix":"10.1111","volume":"15","author":[{"given":"Marta","family":"Hauser","sequence":"first","affiliation":[{"name":"The Zucker Hillside Hospital Glen Oaks NY USA"},{"name":"The Feinstein Institute for Medical Research Manhasset NY USA"},{"name":"Hofstra North Shore LIJ School of Medicine Hempstead NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Britta","family":"Galling","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Psychotherapy and Psychosomatic Medicine University Medical Center Hamburg\u2010Eppendorf (UKE) Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph U","family":"Correll","sequence":"additional","affiliation":[{"name":"The Zucker Hillside Hospital Glen Oaks NY USA"},{"name":"The Feinstein Institute for Medical Research Manhasset NY USA"},{"name":"Hofstra North Shore LIJ School of Medicine Hempstead NY USA"},{"name":"Albert Einstein College of Medicine Bronx NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,7,5]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7610.2006.01615.x"},{"key":"e_1_2_6_3_1","first-page":"87","article-title":"Costs associated with attempted suicide among individuals with bipolar disorder","volume":"13","author":"Stensland MD","year":"2010","journal-title":"J Ment Health Policy Econ"},{"key":"e_1_2_6_4_1","unstructured":"National Vital Statistics Reports Vol. 60 No. 4 January 11 2012. 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