{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T13:28:39Z","timestamp":1758634119164},"reference-count":10,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,12,18]],"date-time":"2013-12-18T00:00:00Z","timestamp":1387324800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bipolar Disorders"],"published-print":{"date-parts":[[2014,3]]},"abstract":"Background<\/jats:title>Although highly controversial, the treatment of obesity with exogenous human chorionic gonadotropin (HCG<\/jats:styled-content>) remains popular in the USA. We report the case of a patient whose first manic episode was associated with the use of HCG<\/jats:styled-content> for weight loss.<\/jats:p><\/jats:sec>Case report<\/jats:title>A 32\u2010year\u2010old female patient was admitted to our psychiatric inpatient unit due to a two\u2010week history of manic symptoms. She had no previous history of manic or hypomanic episodes and had completed a 45\u2010day course of sublingual HCG<\/jats:styled-content> for weight loss immediately prior to the onset of the manic episode. The patient was treated with lithium carbonate and aripiprazole, and progressed with improvement in the symptoms.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>While it is not possible to definitively link the HCG<\/jats:styled-content> use to the development of mania, available evidence suggests that HCG<\/jats:styled-content> may have a contributing role in triggering manic symptomatology.<\/jats:p><\/jats:sec>","DOI":"10.1111\/bdi.12167","type":"journal-article","created":{"date-parts":[[2013,12,18]],"date-time":"2013-12-18T13:12:42Z","timestamp":1387372362000},"page":"204-207","source":"Crossref","is-referenced-by-count":3,"title":["First manic episode associated with use of human chorionic gonadotropin for obesity: a case report"],"prefix":"10.1111","volume":"16","author":[{"given":"Marsal","family":"Sanches","sequence":"first","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences Harris County Psychiatric Center The University of Texas Health Science Center at Houston Houston TX USA"},{"name":"University of Texas Center of Excellence on Mood Disorders Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teresa","family":"Pigott","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences Harris County Psychiatric Center The University of Texas Health Science Center at Houston Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan C","family":"Swann","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences Harris County Psychiatric Center The University of Texas Health Science Center at Houston Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jair C","family":"Soares","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences Harris County Psychiatric Center The University of Texas Health Science Center at Houston Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,12,18]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"12","article-title":"\u201cThere they go again\u201d\u2013hCG and weight loss","volume":"107","author":"Toffle RC","year":"2011","journal-title":"W V Med J"},{"key":"e_1_2_6_3_1","unstructured":"American Society of Bariatric Physicians.ASBP Position on Use of HCG in the Treatment of Obesity 2010. Available from:http:\/\/www.asbp.org\/resources\/uploads\/files\/HCG%20Position%20Statement.pdf[accessed June 2013]."},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(54)92556-8"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2125.1995.tb05779.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1974.03240050021017"},{"key":"e_1_2_6_7_1","unstructured":"Food and Drug Administration.Fraudulent HCG Products for Weight Loss 2011. Available from:http:\/\/www.fda.gov\/Drugs\/ResourcesForYou\/Consumers\/BuyingUsingMedicineSafely\/MedicationHealthFraud\/ucm282465.htm[accessed June 2013]."},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmm019"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-129-3-199808010-00012"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4530(00)00050-0"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.155.3.447-a"}],"container-title":["Bipolar Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fbdi.12167","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bdi.12167","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T13:25:17Z","timestamp":1696339517000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/bdi.12167"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,18]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,3]]}},"alternative-id":["10.1111\/bdi.12167"],"URL":"https:\/\/doi.org\/10.1111\/bdi.12167","archive":["Portico"],"relation":{},"ISSN":["1398-5647","1399-5618"],"issn-type":[{"value":"1398-5647","type":"print"},{"value":"1399-5618","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,18]]}}}