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In the MDcpg\n                      <jats:sup>2020<\/jats:sup>\n                      , these recommendations sit alongside consensus\u2010based recommendations (CBR) that were derived from extensive deliberations of the mood disorders committee, drawing on their expertise and clinical experience. This guideline summary is an abridged version that focuses on major depression. In collaboration with international experts in the field, it synthesises the key recommendations made in relation to the diagnosis and management of major depression.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The depression summary provides a systematic approach to diagnosis, and a logical clinical framework for management. The latter begins with\n                      <jats:italic>Actions<\/jats:italic>\n                      , which include important strategies that should be implemented from the outset. These include lifestyle changes, psychoeducation and psychological interventions. The summary advocates the use of antidepressants in the management of depression as\n                      <jats:italic>Choices<\/jats:italic>\n                      and nominates seven medications that can be trialled as clinically indicated before moving to\n                      <jats:italic>Alternatives<\/jats:italic>\n                      for managing depression. Subsequent strategies regarding Medication include Increasing Dose, Augmenting and Switching (MIDAS). The summary also recommends the use of electroconvulsive therapy (ECT), and discusses how to approach non\u2010response.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      The major depression summary provides up to date guidance regarding the management of major depressive disorder, as set out in the MDcpg\n                      <jats:sup>2020<\/jats:sup>\n                      . The recommendations are informed by research evidence in conjunction with clinical expertise and experience. The summary is intended for use by psychiatrists, psychologists and primary care physicians, but will be of interest to all clinicians and carers involved in the management of patients with depressive disorders.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bdi.13035","type":"journal-article","created":{"date-parts":[[2020,12,20]],"date-time":"2020-12-20T00:34:57Z","timestamp":1608424497000},"page":"788-804","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":120,"title":["The 2020 Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders: Major depression summary"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4524-9091","authenticated-orcid":false,"given":"Gin S.","family":"Malhi","sequence":"first","affiliation":[{"name":"Department of Psychiatry Northern Clinical School Faculty of Medicine and Health The University of Sydney Sydney NSW Australia"},{"name":"Academic Department of Psychiatry Royal North Shore Hospital Northern Sydney Local Health District St Leonards NSW Australia"},{"name":"CADE Clinic Royal North Shore Hospital Northern Sydney Local Health District St Leonards NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8483-8497","authenticated-orcid":false,"given":"Erica","family":"Bell","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Northern Clinical School Faculty of Medicine and Health The University of Sydney Sydney NSW Australia"},{"name":"Academic Department of Psychiatry Royal North Shore Hospital Northern Sydney Local Health District St Leonards NSW Australia"},{"name":"CADE Clinic Royal North Shore Hospital Northern Sydney Local Health District St Leonards NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0853-7959","authenticated-orcid":false,"given":"Ajeet B.","family":"Singh","sequence":"additional","affiliation":[{"name":"The Geelong Clinic Healthscope IMPACT \u2013 Institute for Mental and Physical Health and Clinical Translation School of Medicine Deakin University Geelong VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darryl","family":"Bassett","sequence":"additional","affiliation":[{"name":"Consultant Psychiatrist Perth WA Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5554-6946","authenticated-orcid":false,"given":"Michael","family":"Berk","sequence":"additional","affiliation":[{"name":"IMPACT \u2013 the Institute for Mental and Physical Health and Clinical Translation School of Medicine Barwon Health Deakin University Geelong Australia"},{"name":"Orygen The National Centre of Excellence in Youth Mental Health The Florey Institute and the Department of Psychiatry The University of Melbourne Parkville Vic. 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