{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T18:16:09Z","timestamp":1787508969848,"version":"build-2736575974"},"reference-count":41,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,9,9]],"date-time":"2022-09-09T00:00:00Z","timestamp":1662681600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["MH059929"],"award-info":[{"award-number":["MH059929"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["MH59691"],"award-info":[{"award-number":["MH59691"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["MH59977"],"award-info":[{"award-number":["MH59977"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Bipolar Disorders"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To build a one\u2010year risk calculator (RC) to predict individualized risk for suicide attempt in early\u2010onset bipolar disorder.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Youth numbering 394 with bipolar disorder who completed \u22652 follow\u2010up assessments (median follow\u2010up length\u00a0=\u00a013.1\u2009years) in the longitudinal Course and Outcome of Bipolar Youth (COBY) study were included. Suicide attempt over follow\u2010up was assessed via the A\u2010LIFE Self\u2010Injurious\/Suicidal Behavior scale. Predictors from the literature on suicidal behavior in bipolar disorder that are readily assessed in clinical practice were selected and trichotomized as appropriate (presence past 6\u00a0months\/lifetime history only\/no lifetime history). The RC was trained via boosted multinomial classification trees; predictions were calibrated via Platt scaling. Half of the sample was used to train, and the other half to independently test the RC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There were 249 suicide attempts among 106 individuals. Ten predictors accounted for &gt;90% of the cross\u2010validated relative influence in the model (AUC\u00a0=\u00a00.82; in order of relative influence): (1) age of mood disorder onset; (2) non\u2010suicidal self\u2010injurious behavior (trichotomized); (3) current age; (4) psychosis (trichotomized); (5) socioeconomic status; (6) most severe depressive symptoms in past 6\u00a0months (trichotomized none\/subthreshold\/threshold); (7) history of suicide attempt (trichotomized); (8) family history of suicidal behavior; (9) substance use disorder (trichotomized); (10) lifetime history of physical\/sexual abuse. For all trichotomized variables, presence in the past 6\u00a0months reliably predicted higher risk than lifetime history.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This RC holds promise as a clinical and research tool for prospective identification of individualized high\u2010risk periods for suicide attempt in early\u2010onset bipolar disorder.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bdi.13250","type":"journal-article","created":{"date-parts":[[2022,8,24]],"date-time":"2022-08-24T20:13:46Z","timestamp":1661372026000},"page":"749-757","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["A risk calculator to predict suicide attempts among individuals with\n                    <scp>early\u2010onset<\/scp>\n                    bipolar 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