{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:45:08Z","timestamp":1787013908916,"version":"build-2736575974"},"reference-count":49,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2022,9,25]],"date-time":"2022-09-25T00:00:00Z","timestamp":1664064000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100015459","name":"Danish Cancer Society Research Center","doi-asserted-by":"publisher","award":["R283\u2010A16461"],"award-info":[{"award-number":["R283\u2010A16461"]}],"id":[{"id":"10.13039\/100015459","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004836","name":"Det Frie Forskningsrad","doi-asserted-by":"publisher","award":["7016\u201000048B"],"award-info":[{"award-number":["7016\u201000048B"]}],"id":[{"id":"10.13039\/501100004836","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003554","name":"Lundbeckfonden","doi-asserted-by":"publisher","award":["R344\u20102020\u20101073"],"award-info":[{"award-number":["R344\u20102020\u20101073"]}],"id":[{"id":"10.13039\/501100003554","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003554","name":"Lundbeckfonden","doi-asserted-by":"publisher","award":["R358\u20102020\u20102341"],"award-info":[{"award-number":["R358\u20102020\u20102341"]}],"id":[{"id":"10.13039\/501100003554","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009708","name":"Novo Nordisk Fonden","doi-asserted-by":"publisher","award":["NNF20SA0062874"],"award-info":[{"award-number":["NNF20SA0062874"]}],"id":[{"id":"10.13039\/501100009708","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010078","name":"Region Midtjylland","doi-asserted-by":"publisher","award":["1\u201036\u201072\u20104\u201020"],"award-info":[{"award-number":["1\u201036\u201072\u20104\u201020"]}],"id":[{"id":"10.13039\/501100010078","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006751","name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006751","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004837","name":"Ministerio de Ciencia e Innovaci\u00f3n","doi-asserted-by":"publisher","award":["PI15\/00283,PI18\/00805"],"award-info":[{"award-number":["PI15\/00283,PI18\/00805"]}],"id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002924","name":"Federaci\u00f3n Espa\u00f1ola de Enfermedades Raras","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002924","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Bipolar Disorders"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The use of electroconvulsive therapy (ECT) in the treatment of bipolar disorder (BD) remains poorly described. Based on data from Danish registries with complete nationwide coverage, this study of patients with incident BD aimed to describe when, how, and for whom ECT is used in the context of BD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We identified patients receiving their first diagnosis of BD in the period from 2008 to 2018, who subsequently received ECT. Descriptive statistics were used to clarify when, how, and for whom ECT is used.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We identified 1338 patients with incident BD who subsequently received ECT. The median age at the first ECT session was 50.6\u2009years (interquartile range [IQR]: 26.4), and 62% of those treated with ECT were female. The median time from the diagnosis of BD to the first ECT treatment was 0.6\u2009years (IQR: 2.6), and 58% of the patients receiving ECT had the first treatment within the first year after being diagnosed with BD. The most common indication for the first ECT treatment was depression (mainly non\u2010psychotic depression), followed by mania (mainly psychotic mania). The first ECT session was typically provided to inpatients (97%), upon patient consent (98%) and with bilateral electrode placement (60%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A substantial proportion of the patients with incident BD who receive ECT require this treatment within the first year after the diagnosis. The most common indication for ECT is depression followed by (psychotic) mania. Inpatient voluntary ECT using bilateral electrode placement is the most common form of administration.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bdi.13254","type":"journal-article","created":{"date-parts":[[2022,9,5]],"date-time":"2022-09-05T20:53:17Z","timestamp":1662411197000},"page":"817-825","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Electroconvulsive therapy following incident bipolar disorder: When, how, and for whom?"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6352-5179","authenticated-orcid":false,"given":"Estela","family":"Salagre","sequence":"first","affiliation":[{"name":"Bipolar and Depressive Disorders Unit Hospital Clinic, Institute of Neurosciences, University of Barcelona, IDIBAPS, CIBERSAM  Barcelona Spain"},{"name":"Department of Affective Disorders Aarhus University Hospital\u2014Psychiatry  Aarhus Denmark"},{"name":"Department of Clinical Medicine Aarhus University  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Rohde","sequence":"additional","affiliation":[{"name":"Department of Affective Disorders Aarhus University Hospital\u2014Psychiatry  Aarhus Denmark"},{"name":"Department of Clinical Medicine Aarhus University  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0548-0053","authenticated-orcid":false,"given":"Eduard","family":"Vieta","sequence":"additional","affiliation":[{"name":"Bipolar and Depressive Disorders Unit Hospital Clinic, Institute of Neurosciences, University of Barcelona, IDIBAPS, CIBERSAM  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8032-6208","authenticated-orcid":false,"given":"S\u00f8ren D.","family":"\u00d8stergaard","sequence":"additional","affiliation":[{"name":"Department of Affective Disorders Aarhus University Hospital\u2014Psychiatry  Aarhus Denmark"},{"name":"Department of Clinical Medicine Aarhus University  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,9,25]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/bdi.13036"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2021.21040351"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)12705-5"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2020.20030238"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2014.13111517"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2021.04.023"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/acps.13209"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/1403494810390728"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/YCT.0000000000000586"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/brb3.37"},{"key":"e_1_2_8_12_1","unstructured":"VidebechP HjerrildS J\u00f8rgensenA J\u00f8rgensenMB Danish psychiatric association.ECT guideline 2020.2020. Accessed October 4 2021.https:\/\/registercentrum.blob.core.windows.net\/ect\/r\/DPS\u2010ECT\u2010vejledning\u20102020\u2010rJgD5hvQ0I.pdf"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/1403494810387965"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/1403494811401482"},{"key":"e_1_2_8_15_1","unstructured":"The Danish Health and Medicines Authority.Elektroconvulsiv terapi (ECT\u2010behandling) og d\u00f8dsfald \u2010 en udredning K\u00f8benhavn: Sundhedsstyrelsen.2010. Accessed October 4 2021.http:\/\/www.sst.dk"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2005.07.015"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/YCT.0000000000000736"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/bdi.12976"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00406-009-0085-2"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2015.04.024"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2017.17090972"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/bdi.12793"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2014.05.012"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1461145703003341"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1906193"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/bdi.12860"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/YCT.0000000000000790"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1177\/0706743717738492"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/YCT.0000000000000243"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2014.11.058"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.2174\/1570159X14666161017233642"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2009.09010105"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.3109\/09540261.2010.514601"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2016.15091119"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291704003307"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2008.11.012"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2010.10.033"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(99)00111-1"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/gps.4465"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina57060587"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.jcp.0000095344.32154.d3"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2006.10.008"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.187.1.43"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1177\/0891988707311027"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1097\/YCT.0000000000000755"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/bdi.13005"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2021.03.005"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1186\/1745-0179-5-4"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0924-9338(99)80685-3"},{"issue":"2","key":"e_1_2_8_50_1","first-page":"A4578","article-title":"The validity of the schizophrenia diagnosis in the Danish psychiatric central research register is good","volume":"60","author":"Uggerby P","year":"2013","journal-title":"Dan Med J"}],"container-title":["Bipolar Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bdi.13254","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/bdi.13254","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bdi.13254","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T17:55:45Z","timestamp":1692467745000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/bdi.13254"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,25]]},"references-count":49,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["10.1111\/bdi.13254"],"URL":"https:\/\/doi.org\/10.1111\/bdi.13254","archive":["Portico"],"relation":{},"ISSN":["1398-5647","1399-5618"],"issn-type":[{"value":"1398-5647","type":"print"},{"value":"1399-5618","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,25]]},"assertion":[{"value":"2022-09-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}