{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T21:09:52Z","timestamp":1778879392010,"version":"3.51.4"},"reference-count":5,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,11,27]],"date-time":"2023-11-27T00:00:00Z","timestamp":1701043200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Bipolar Disorders"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We present a case of disulfiram\u2010induced mania in a patient with both alcohol use disorder (AUD) and psychostimulant use disorder (PUD), without a history of psychosis or mania. This acute presentation may be linked to the increased dopamine levels caused by disulfiram metabolism. Our patient developed manic symptoms 10\u2009days after starting disulfiram, prescribed to treat the AUD. It should be noted that the symptoms resolved rapidly after disulfiram cessation during hospitalization. Disulfiram use is an effective treatment for alcohol dependence. However, there are safety concerns associated with it and it requires close monitoring, particularly in patients with a history of mania, psychosis, or psychostimulant use.<\/jats:p>","DOI":"10.1111\/bdi.13397","type":"journal-article","created":{"date-parts":[[2023,11,28]],"date-time":"2023-11-28T00:45:49Z","timestamp":1701132349000},"page":"395-397","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Aversive agents: Think twice. A case report on disulfiram\u2010induced mania"],"prefix":"10.1111","volume":"26","author":[{"given":"Mar\u00eda Fernanda","family":"Gonz\u00e1lez\u2010Romero","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Institute of Psychiatry and Mental Health Hospital General Universitario Gregorio Mara\u00f1\u00f3n  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5983-1664","authenticated-orcid":false,"given":"Jos\u00e9 Mar\u00eda","family":"Mart\u00ednez\u2010\u00c1vila","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Institute of Psychiatry and Mental Health Hospital General Universitario Gregorio Mara\u00f1\u00f3n  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Moloney","sequence":"additional","affiliation":[{"name":"Department of Geriatric Medicine Mercy University Hospital  Cork Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ignacio","family":"Garc\u00eda\u2010Cabeza","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Institute of Psychiatry and Mental Health Hospital General Universitario Gregorio Mara\u00f1\u00f3n  Madrid Spain"},{"name":"Department of Medicine Universidad Complutense de Madrid  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,11,27]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2007.08.035"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2021.10.209"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/tpsy.tpsy_17_20"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/ADM.0000000000000992"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-021-01670-3"}],"container-title":["Bipolar Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bdi.13397","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T04:40:16Z","timestamp":1717994416000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/bdi.13397"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,27]]},"references-count":5,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1111\/bdi.13397"],"URL":"https:\/\/doi.org\/10.1111\/bdi.13397","archive":["Portico"],"relation":{},"ISSN":["1398-5647","1399-5618"],"issn-type":[{"value":"1398-5647","type":"print"},{"value":"1399-5618","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,27]]},"assertion":[{"value":"2023-11-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}