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While diverse factors can impact these impairments, sleep disturbance is considered a key component. This cross\u2010sectional report aimed to analyze the association between subjective sleep characteristics and objective cognitive impairment in two independent samples of remitted outpatients with BD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Baseline data, including neuropsychological test performances and questionnaire\u2010based sleep quality, subjective cognitive complaints, and mood ratings, were pooled from two clinical trials. Eighteen\u2010 to sixty\u2010four\u2010year\u2010old fully or partially remitted outpatients with BD were divided into two independent cohorts: (i) newly diagnosed patients classified as cognitively impaired (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200940) or normal (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200958) according to hierarchical cluster analysis and matching healthy controls (HC) (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200980), as well as (ii) patients with longer duration of illness prescreened for cognitive impairment (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009115) and matching HC (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200975). Subjective sleep quality was assessed with the Pittsburgh Sleep Quality Index (PSQI). Correlational and multiple linear regression analyses investigated associations between cognition and sleep.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In age\u2010, sex\u2010, and medication\u2010adjusted regression analyses, subjectively reported sleep quality (PSQI total score) was not associated with objective cognitive impairment globally or across domains in any cohort. Instead, worse subjective sleep quality was associated with more subjective cognitive complaints, greater subsyndromal depression symptoms, and receiving antipsychotic medication.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our findings support the view that objective cognitive impairments in remitted patients with BD, whether newly diagnosed or with longer illness duration, may not be solely attributable to subjectively reported sleep disturbances. This adds to emerging evidence suggesting cognition as a relevant treatment target in BD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bdi.70051","type":"journal-article","created":{"date-parts":[[2025,8,23]],"date-time":"2025-08-23T03:40:35Z","timestamp":1755920435000},"page":"435-448","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Disentangling Subjective Sleep and Objective Cognition: Insights From Two Independent Cross\u2010Sectional Cohorts of Remitted Bipolar Disorder"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3415-8098","authenticated-orcid":false,"given":"Jeff","family":"Zarp","sequence":"first","affiliation":[{"name":"Copenhagen Affective Disorder Research Centre (CADIC), Psychiatric Centre Copenhagen, Frederiksberg Hospital  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7781-8853","authenticated-orcid":false,"given":"Hanne Lie","family":"Kj\u00e6rstad","sequence":"additional","affiliation":[{"name":"Copenhagen Affective Disorder Research Centre (CADIC), Psychiatric Centre Copenhagen, Frederiksberg Hospital  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Nesje","family":"Porten","sequence":"additional","affiliation":[{"name":"Department of Psychology University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9377-9436","authenticated-orcid":false,"given":"Lars Vedel","family":"Kessing","sequence":"additional","affiliation":[{"name":"Copenhagen Affective Disorder Research Centre (CADIC), Psychiatric Centre Copenhagen, Frederiksberg Hospital  Copenhagen Denmark"},{"name":"Department of Clinical Medicine University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2572-1384","authenticated-orcid":false,"given":"Kamilla Woznica","family":"Miskowiak","sequence":"additional","affiliation":[{"name":"Copenhagen Affective Disorder Research Centre (CADIC), Psychiatric Centre Copenhagen, Frederiksberg Hospital  Copenhagen Denmark"},{"name":"Department of Psychology University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,8,22]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291714000439"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2016.08.018"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/bdi.12148"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2023.101927"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.162.1.50"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2008.08010098"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1037\/a0028233"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn.2017.55"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2017.01.001"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2023.01.114"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1037\/a0038655"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2014.07.017"},{"key":"e_1_2_10_15_1","unstructured":"O. 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