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By employing phylogenetic analysis, molecular HIV surveillance can identify individuals and their positions within networks of HIV transmission. While the primary aim of molecular surveillance is to yield public health benefits, such as linking people to care and reducing transmission, it also poses risks and potential infringements on individual privacy and liberty. This paper examines the ethical implications of using phylogenetics to identify individuals involved in multiple transmission events in high\u2010income countries. Although public health responses tailored to such individuals can significantly reduce further transmission, these individuals often face multiple intersecting vulnerabilities and bear the greatest risks associated with molecular surveillance. We analyze the risks related to privacy, stigma, mistrust, criminalization, and liberty infringements, alongside the benefits of preventing further transmission and increasing healthcare engagement for people living with HIV. We conclude by outlining plausible and ethically acceptable policy options for molecular surveillance practice.<\/jats:p>","DOI":"10.1111\/bioe.70011","type":"journal-article","created":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T08:30:15Z","timestamp":1753173015000},"page":"762-771","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Ethics of Identifying Individuals Involved in HIV Transmission Events by Phylogenetics in Molecular Surveillance"],"prefix":"10.1111","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-5009-2835","authenticated-orcid":false,"given":"Francisca","family":"Faber","sequence":"first","affiliation":[{"name":"Division of Neuropathology and Neurochemistry, Department of Neurology Medical University of Vienna Vienna 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